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posted by takyon on Friday June 29 2018, @02:20AM   Printer-friendly
from the prick dept.

Submitted via IRC for Fnord666

Research finds four keys to piercing skin without hurting

Researchers at The Ohio State University believe we can learn from nature's design of the mosquito to create a painless microneedle for medical purposes.

"Mosquitoes must be doing something right if they can pierce our skin and draw blood without causing pain," said Bharat Bhushan, Ohio Eminent Scholar and Howard D. Winbigler Professor of mechanical engineering at Ohio State.

"We can use what we have learned from mosquitoes as a starting point to create a better microneedle."

In a recently published paper, Bhushan and his colleagues reported on their detailed analysis of the mosquito's proboscis -- the part that feeds on us. They identified four keys to how the insects pierce us without pain: use of a numbing agent; a serrated design to the "needle"; vibration during the piercing; and a combination of soft and hard parts on the proboscis.

Lessons from mosquitoes' painless piercing (DOI: 10.1016/j.jmbbm.2018.05.025) (DX)


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  • (Score: 2) by JoeMerchant on Friday June 29 2018, @02:39AM (7 children)

    by JoeMerchant (3937) on Friday June 29 2018, @02:39AM (#700090)

    The really impressive thing about mosquitoes is how their proboscis feels and/or smells its way into an active blood vessel.

    There's a whole lot more going on in a mosquito than anybody will ever be willing to pay for in a disposable hypodermic needle.

    --
    🌻🌻 [google.com]
    • (Score: 0) by Anonymous Coward on Friday June 29 2018, @03:05AM

      by Anonymous Coward on Friday June 29 2018, @03:05AM (#700093)

      A real-life gom jabbar would command a high price. https://www.youtube.com/watch?v=QrCfivcQe48 [youtube.com] (scene from Dune)

    • (Score: 3, Interesting) by MichaelDavidCrawford on Friday June 29 2018, @05:55AM (3 children)

      I am a notoriously "tough stick". My Happy Pills might destroy my liver someday so I need regular CBC counts. That I'm a dirty old man now makes me a candidate for diabetes, heart attack and stroke. I have such great psychogenic pokydipsia that my very first symptom of hyponatremia may very well be sudden death. Last but not least I have a chronic vitamin D deficiency that even prescription Ergocalciferol won't give me strong teeth and bones.

      What gets me down is not the initial stick but the way my nurses move their needles in and out and side to side as they vainly attemp to corner my vein.

      In the ER one night my nurse was so stymied by my small wiggly veins that she wheeled out the heavy artillery:

      A phenomenally expensive device that projected my veins onto my arm with a diode laser. It's was so powerful that as I moved my arm around it updated its image in real time.

      --
      Yes I Have No Bananas. [gofundme.com]
      • (Score: 0) by Anonymous Coward on Friday June 29 2018, @07:26AM (1 child)

        by Anonymous Coward on Friday June 29 2018, @07:26AM (#700154)
        Ergocalciferol is vitamin D2. For strong teeth and bones you might have better luck with Cholecalciferol (vitamin D3) to absorb calcium and vitamin K2 to send the calcium to your teeth and bones. Also watch the ratio of your Calcium to Magnesium intake.
        • (Score: 2) by RS3 on Friday June 29 2018, @01:11PM

          by RS3 (6367) on Friday June 29 2018, @01:11PM (#700222)

          Strontium and phosphorus for bones too.

      • (Score: 3, Interesting) by All Your Lawn Are Belong To Us on Friday June 29 2018, @03:01PM

        by All Your Lawn Are Belong To Us (6553) on Friday June 29 2018, @03:01PM (#700241) Journal

        Interesting. I am a tough stick also, often. My record in one setting was 11 sticks to get a good vein. A couple of times it has been 7. On my record they used an ultrasound to spot the vein.
        It's lucky that I'm so used to that by now it usually doesn't matter - the staff are far more apoogetic to me than they need be because I know it is my veins and not their skill that is the issue at hand.

        --
        This sig for rent.
    • (Score: 0) by Anonymous Coward on Friday June 29 2018, @06:23AM (1 child)

      by Anonymous Coward on Friday June 29 2018, @06:23AM (#700144)

      Since the mosquito has evolved an excellent needle, vein finding, & blood collecting mechanism, why aren't we engineering mosquitos that include various human diagnostic tests? A genetically engineered mosquito bites you under controlled conditions, takes some blood, then the mosquito turns color (or anything easy to sense) if your blood level of factor ___ is high and another color if it's low.

      Or, maybe the mosquito is bred so that the anti-coagulant (aka bug saliva) doesn't leave people with an itchy bump, and after the bite the mosquito is sacrificed and the blood moved to a blood testing machine that works with tiny samples.

      • (Score: 1) by khallow on Friday June 29 2018, @06:43AM

        by khallow (3766) Subscriber Badge on Friday June 29 2018, @06:43AM (#700148) Journal

        A genetically engineered mosquito bites you under controlled conditions,

        And then determines what health care and life style products to sell you. I can't imagine why it wouldn't be a massively good idea. This documentary [wikipedia.org] highlights some of the high points of the idea.

  • (Score: 3, Insightful) by Snotnose on Friday June 29 2018, @03:39AM (6 children)

    by Snotnose (1623) on Friday June 29 2018, @03:39AM (#700101)

    Trade a couple seconds of a pinprick for a week's worth of scratching.

    Too lazy to google it, but I'm pretty sure you don't notice the mosquito using his dinner fork because she sprays a numbing agent to the skin just before saying grace.

    --
    When the dust settled America realized it was saved by a porn star.
    • (Score: 5, Informative) by takyon on Friday June 29 2018, @03:47AM (2 children)

      by takyon (881) <takyonNO@SPAMsoylentnews.org> on Friday June 29 2018, @03:47AM (#700106) Journal

      That simple Google search would have stopped you from spreading misinformation.

      https://www.google.com/search?q=what+causes+mosquito+bites+to+itch [google.com] (search suggested by GOOG, I was typing "what causes mosquito pain")

      https://www.terminix.com/pest-control/mosquitoes/bites/why-do-bites-itch/ [terminix.com]

      At the same time your blood is pumping out of your body, the mosquito pumps saliva in. This saliva acts as an anticoagulant, which prevents your blood from clotting at the site of the puncture. This allows the mosquito to feed quickly, giving her a better chance of stealing away with your blood before you notice and splat her on your arm. This saliva is specifically why mosquito bites itch – you have an allergic reaction to it, resulting in the telltale bump and itching associated with mosquito bites.

      https://www.medicalnewstoday.com/articles/320979.php [medicalnewstoday.com]

      The swelling around the bite is caused by histamine, which is produced by the immune system. Histamine increases blood flow and white blood cell count around the affected area, which causes inflammation or swelling. Mosquito bites itch because histamine also sends a signal to the nerves around the bite.

      Not applicable to a microneedle patch.

      From an eerily similar article:

      Painless needle mimics a mosquito’s bite [newscientist.com]

      Contrary to popular belief, a mosquito bite does not hurt. It is the anticoagulant saliva that the creature injects to stop your blood clotting that causes inflammation and pain.

      The new needle has an inner diameter of around 25 microns and an external diameter of 60 microns, which is about the same size as a mosquito’s mouthpart. Its size and the fact that it works by suction, makes it painless. To compare, a conventional syringe needle has an outer diameter of around 900 microns.

      --
      [SIG] 10/28/2017: Soylent Upgrade v14 [soylentnews.org]
      • (Score: -1, Troll) by Anonymous Coward on Friday June 29 2018, @05:58AM (1 child)

        by Anonymous Coward on Friday June 29 2018, @05:58AM (#700141)

        This allows the mosquito to feed quickly, giving her a better chance of stealing away with your blood before you notice and splat her on your arm.

        Did they just assume the mosquito's gender? Such bigotry... Maybe the mosquito identifies as a male?

    • (Score: 0) by Anonymous Coward on Friday June 29 2018, @04:12AM

      by Anonymous Coward on Friday June 29 2018, @04:12AM (#700109)

      No need to Google: that's in the summary.

    • (Score: 2) by cmdrklarg on Friday June 29 2018, @05:44PM (1 child)

      by cmdrklarg (5048) Subscriber Badge on Friday June 29 2018, @05:44PM (#700294)

      Best way to get rid of the itch is to run water over it as hot as you can stand for 10-15 seconds. A hot shower usually does the trick. Obviously don't use water hot enough to scald.

      A washcloth soaked in hot water works for areas that are harder to get under the hot water tap, or if a shower isn't readily available.

      --
      The world is full of kings and queens who blind your eyes and steal your dreams.
      • (Score: 2) by Snotnose on Friday June 29 2018, @10:01PM

        by Snotnose (1623) on Friday June 29 2018, @10:01PM (#700394)

        Just what I never wanted. Trade a week's worth of itching to a lifetime of scarring :)

        --
        When the dust settled America realized it was saved by a porn star.
  • (Score: 2) by ese002 on Friday June 29 2018, @07:07PM

    by ese002 (5306) on Friday June 29 2018, @07:07PM (#700318)

    They make much bigger holes and they don't cause pain either.

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