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from the you-say-MuTaTo,-I-say-MuTayTo dept.
Accelerated Evolution Biotechnologies Ltd. (AEBi) is making some grandiose claims regarding a new approach to fighting cancer they have been developing dubbed "MuTaTo" (multi-target toxin).
"We believe we will offer in a year's time a complete cure for cancer."
most anti-cancer drugs attack a specific target on or in the cancer cell, [Dr. Ilan Morad] explained. Inhibiting the target usually affects a physiological pathway that promotes cancer. Mutations in the targets – or downstream in their physiological pathways – could make the targets not relevant to the cancer nature of the cell, and hence the drug attacking it is rendered ineffective.
In contrast, MuTaTo is using a combination of several cancer-targeting peptides for each cancer cell at the same time, combined with a strong peptide toxin that would kill cancer cells specifically. By using at least three targeting peptides on the same structure with a strong toxin, Morad said, "we made sure that the treatment will not be affected by mutations;
He continues
"The probability of having multiple mutations that would modify all targeted receptors simultaneously decreases dramatically with the number of targets used. Instead of attacking receptors one at a time, we attack receptors three at a time – not even cancer can mutate three receptors at the same time."
It seems there is a new cancer cure regularly, but hope springs eternal, in this case the research is out of a petri dish and into animal testing.
Morad said that so far, the company has concluded its first exploratory mice experiment, which inhibited human cancer cell growth and had no effect at all on healthy mice cells, in addition to several in-vitro trials. AEBi is on the cusp of beginning a round of clinical trials which could be completed within a few years and would make the treatment available in specific cases.
What say you? 'We're saved!' or 'wake me when it gets through Phase III clinical trials'?
(Score: 0) by Anonymous Coward on Wednesday January 30 2019, @12:50AM (2 children)
They did one unpublished crappy mouse experiment and now say a cure is on the way?
(Score: 2) by ikanreed on Wednesday January 30 2019, @12:53AM
Yeah "Show's promise" for cancer treatment is useless. Medical white noise.
It's like having a "novel technique" for fusion and making a press release saying "we've fused successfully". Great, you and a kid with a homemade tokamak both got the same results.
(Score: 3, Insightful) by MostCynical on Wednesday January 30 2019, @01:15AM
They are only really looking to cure their lack of funding for the next experiments.
"I guess once you start doubting, there's no end to it." -Batou, Ghost in the Shell: Stand Alone Complex
(Score: 0) by Anonymous Coward on Wednesday January 30 2019, @12:58AM (7 children)
The US has a "right to try" policy now, thanks to Trump, actually, so people can actually try these technologies much sooner hopefully.
(Score: 0) by Anonymous Coward on Wednesday January 30 2019, @01:03AM (6 children)
https://www.statnews.com/2019/01/29/right-to-try-patients-still-arent-getting-treatment/ [statnews.com]
(Score: 2) by RS3 on Wednesday January 30 2019, @01:12AM (5 children)
We now have a direct right to try treatments, but it does not mean healthcare providers are forced to give you the treatment, it just means the governmental (FDA, etc.) regulations have been relaxed.
(Score: -1, Troll) by Anonymous Coward on Wednesday January 30 2019, @01:19AM (4 children)
You want to be able to *force* a doctor to give you some wierd ass treatment? Im not in favor of the fda having any role in assessing efficacy whatsoever... but that is way beyond how dumb I thought people could get.
(Score: 2) by RS3 on Wednesday January 30 2019, @02:00AM (3 children)
> You want to be able to *force* a doctor to give you some wierd ass treatment?
I wrote no such thing. I don't quite understand your response but I'll chalk it up to you being AC. Ironic you calling me "dumb".
That you somehow misunderstood what I wrote, then replied based on your incorrect belief, is a great example of where so much strife comes from in today's world.
(Score: -1, Troll) by Anonymous Coward on Wednesday January 30 2019, @02:09AM (2 children)
(Score: 2) by RS3 on Wednesday January 30 2019, @02:48AM (1 child)
My statement stands. No further meaning (that you seem to read in) is meant nor implied. I'm not responsible for your imagination. I don't know what world you live in, but I bet you're a frustrating person to be around if you extrapolate that way.
Perhaps your difficulty is that you're looking at it as you quoted it, rather than in the context of what I was responding to?
Perhaps you have logical problems? You do understand the statement: "all horses are animals, but not all animals are horses"??
(Score: -1, Troll) by Anonymous Coward on Wednesday January 30 2019, @02:15PM
Why did you bring up the possibility that "healthcare providers are forced to give you the treatment"? Why contemplate this unless you thought it was desirable for some reason?
Perhaps people want to buy a sex change operation and pay with gold their grandfather bequeathed to them. In that case I can imagining wanting to "force" the doctor to do something.
(Score: 0) by Anonymous Coward on Wednesday January 30 2019, @02:44AM
Total bullshit. The next move will be "oh, we are so close, but we are short of money!" And when they'll secure their funding, they will say "Oops. it didn't worked as we expected it to. Actually, it is even worser than already existing drugs. With science, you don't always get what you want. Also, give us some more money, please, this time we'll do it for sure!"
(Score: 2) by Phoenix666 on Wednesday January 30 2019, @02:55AM (2 children)
Wake me when Phase III trials have been completed successfully and it has been demonstrated not to unleash zombies on the world (aka I Am Legend).
On a different note, if they did succeed I would say more than wipe out Israel's karmic deficit and earn them free drinks anywhere for the next 100 years.
Washington DC delenda est.
(Score: 2) by RandomFactor on Sunday February 03 2019, @01:25AM (1 child)
To be fair, there are endless hoards of rednecks prepped and ready [texasbowhunter.com] for the coming zombie apocalypse
В «Правде» нет известий, в «Известиях» нет правды
(Score: 2) by Phoenix666 on Sunday February 03 2019, @10:26PM
This morning we had to thread through shuffling, meandering figures walking down the block and I realized the zombie apocalypse is already upon us: they were too busy burying their noses in their smartphones to watch where they were going.
Washington DC delenda est.
(Score: 2) by Ken_g6 on Wednesday January 30 2019, @04:56AM
Instead of taking just one drug, take three and hope each cancer cell is killed by at least one.
Sounds likely to increase remission rates and decrease recurrence.
Sounds like an even better strategy for superbugs (antibiotic-resistant bacteria), though. The problem with cancer (so far) is being able to find three drugs that target one cancer. And work well together. (Immunotherapy and traditional chemo probably wouldn't work well together, for instance.)
(Score: 0) by Anonymous Coward on Wednesday January 30 2019, @03:26PM
If it really ever proves to be a cure for cancer, expect it to disappear quicker than Kennedy trying to release the grip of our country from tyrannical hands. Nothing that takes money outta the pockets of big pharma and the medical industry as a whole will ever see the light of day.
(Score: 1) by Tokolosh on Wednesday January 30 2019, @04:52PM
https://www.youtube.com/watch?v=ZXcC1M2zFSA [youtube.com]
(Score: 2) by RandomFactor on Friday February 01 2019, @03:02AM
https://www.livescience.com/64648-israeli-scientists-cancer-cure-unlikely.html [livescience.com]
В «Правде» нет известий, в «Известиях» нет правды