Submitted via IRC for TheMightyBuzzard
For the first time, scientists were able to correct the genetic mutation that causes sickle cell disease in stem cells.
In a collaborative effort, researchers at UC Berkeley, UC San Francisco Benioff Children's Hospital Oakland Research Institute (CHORI), and the University of Utah School of Medicine fixed the mutation in modified stem cells from patients with the condition using a CRISPR/Cas9 gene editing approach.
The study, "Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells," was published in the journal Science Translational Medicine.
The scientists hope to re-infuse patients with the modified stem cells and alleviate disease symptoms.
"We're very excited about the promise of this technology," Jacob Corn, senior author on the study and scientific director of the Innovative Genomics Initiative at UC Berkeley, said in a news release. "There is still a lot of work to be done before this approach might be used in the clinic, but we're hopeful that it will pave the way for new kinds of treatment for patients with sickle cell disease."
(Score: 4, Funny) by Snotnose on Sunday October 23 2016, @03:05AM
Means you have to have the cops shoot more innocent darkies to make up for those who survive sickle cell! Dafuq you thinking scientists, we have standards to maintain here!
When the dust settled America realized it was saved by a porn star.
(Score: 3, Insightful) by Snotnose on Sunday October 23 2016, @03:09AM
Ayup, another moderation lottery here. Insightful, funny, sad, troll, something else. Place your bets here folks, just wish I could make money off this comedy gold.
When the dust settled America realized it was saved by a porn star.
(Score: 2) by Runaway1956 on Sunday October 23 2016, @03:09AM
Amusing - I like dark humor. But, someone will be along soon to mod you a troll.
(Score: 2) by Snotnose on Sunday October 23 2016, @03:11AM
Seems to me being modded a troll knocks you down to 0 points, even if you were +5 insightful. Or am I not hitting F5 on my own posts often enough?
When the dust settled America realized it was saved by a porn star.
(Score: 3, Informative) by Runaway1956 on Sunday October 23 2016, @03:25AM
I've never looked into the mechanics, but I think it's straight math. +1 -1 +1 +1 -1 = 1
The only mod that really screws things up, is the spam mod. Think that's -25 - mod bombers did that a few times early on, and brought a person's karma down to the pits of hell. Those abuses were quickly addressed, and we don't see that now.
So, if you find a post modded to -5, that means at least five people have down modded it, and the descriptor tells you which down mod was used the most.
(Score: 3, Informative) by The Mighty Buzzard on Sunday October 23 2016, @10:37AM
Spam's only -1 to the comment same as everything else. It's a -10 hit to the user's karma though.
My rights don't end where your fear begins.
(Score: 2) by The Mighty Buzzard on Sunday October 23 2016, @10:43AM
Just for kicks, at the time of this posting the post in question has two Offtopic, one Informative, and two Funny moderations for a net total of +1.
My rights don't end where your fear begins.
(Score: 0) by Anonymous Coward on Sunday October 23 2016, @07:25AM
ur moderated as troll. i up-moderated parent because it was classic.