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from the breathing-new-life-into-asthma-treatments dept.
A new study led by the University of Leicester to understand how to improve the health of severe asthma patients has made a breakthrough finding.
Researchers have described their discovery as a 'paradigm shift' in understanding the life-threatening condition.
The international team from the Department of Infection, Immunity and Inflammation, University of Leicester, and the Department of Pharmaceutical Sciences, Jefferson School of Pharmacy, Thomas Jefferson University, discovered the presence of increased amounts of a protein -- called PP5 -- in the lungs of severe asthma patients.
They found that PP5 blocks the effects of the best medicines in improving the condition.
This now provides researchers with a target in order to try and help improve the symptoms of the condition in sufferers. The team has published their findings in the journal Allergy -- the European Journal of Allergy and Clinical Immunology.
The protein PP5 blocks the action of anti-asthma medication in the lungs, so new treatments might be found that skirt the protein.
An abstract is available: Protein phosphatase 5 mediates corticosteroid insensitivity in airway smooth muscle in patients with severe asthma. Allergy, 2016; DOI: 10.1111/all.13003
(Score: 0) by Anonymous Coward on Sunday October 30 2016, @08:57PM
I want the people associated with this press release to stay away from me.