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posted by cmn32480 on Friday January 06 2017, @04:54PM   Printer-friendly
from the maybe-it-is-a-dinopeptic-germ dept.

In a population-based study from Scotland, use of commonly-prescribed acid suppression medications such as proton pump inhibitors (PPIs) was linked with an increased risk of intestinal infections with C. difficile and Campylobacter bacteria, which can cause considerable illness.

Compared with individuals in the community who did not take acid suppression medications, those who did had 1.7-times and 3.7-times increased risks of C. difficile and Campylobacter, respectively. Among hospitalized patients, those using the medications had 1.4-times and 4.5-times increased risks, respectively.

Although acid suppression therapy is often considered relatively free from side effects, the findings suggest that there are significant adverse gastrointestinal consequences of their use. "Users of these medications should be particularly vigilant about food hygiene as the removal of stomach acid makes them more easily infected with agents such as Campylobacter, which is commonly found on poultry," said Prof. Thomas MacDonald, senior author of the British Journal of Clinical Pharmacology study.

DOI: 10.1111/bcp.13205

Maybe they should cut back on haggis and chips instead.


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  • (Score: 2) by butthurt on Friday January 06 2017, @08:19PM

    by butthurt (6141) on Friday January 06 2017, @08:19PM (#450392) Journal

    [...] a little bit of diluted apple cider vinegar [theoretically] ups the acid content in your stomach [...]

    I was about to post that the pH of stomach acid is much lower than that of vinegar, let alone diluted vinegar. However, I seem to have been mistaken in believing that:

    The pH of your stomach varies, from 1-2 up to 4-5.
    [...]
    the proteases that cleave proteins work best in an acidic environment or low pH, so after a high-protein meal, your stomach pH may drop to as low as 1 or 2. However, buffers quickly raise the pH back to 3 or 4. After the meal has been digested, your stomach pH returns to a resting level of about 4 or 5.

    --
    http://chemistry.about.com/od/lecturenoteslab1/a/Stomach-Ph.htm [about.com]

    Vinegar has a pH of 2.2, according to Dr. Anne Marie Helmenstine, a contributor to About.com.

    -- https://www.reference.com/science/ph-vinegar-c215ade97402d6ca [reference.com]

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