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UK scientists say they have conducted an unprecedented, long-term study showing a link between Roundup - one of the most widely used herbicides in the world - and severe liver damage in test rats.
The research sparked further debate in the international scientific community over the potential health hazards to people caused by exposure to the well-known weed killer.
Scientists from King's College London, whose findings were published in the journal, Nature , earlier this month, said their tests used cutting-edge technology to demonstrate that "extremely low doses" of the herbicide administered to rats through their drinking water had caused "non-alcoholic fatty liver disease (NAFLD)" over a two-year period.
NAFLD can lead to more serious liver disease such as cirrhosis, and increases the risk of other illnesses including diabetes, heart attacks and strokes.
"The study is unique in that it is the first to show a causative link between consumption of Roundup at a real-world environmental dose and a serious disease condition," the report said.
In recent years, there have been an increasing number of studies alleging links between herbicides - used to help grow genetically modified crops - to a wide range of health issues including birth defects, reproductive and neurological problems, cancer, and even DNA damage. Monsanto, the maker of Roundup, has repeatedly denied the accusations , insisting the product is safe for humans. A number of scientists and researchers say there has been insufficient evidence to prove herbicides cause health problems for people.
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(Score: 2, Interesting) by Anonymous Coward on Tuesday January 24 2017, @07:03AM
One thing to note is while Roundup contains glyphosate, glyphosate isn't the only chemical it contains. So they can make all sorts of truthful claims that glyphosate isn't that toxic for a pesticide for humans at X concentrations despite Roundup itself being far more dangerous and toxic.
https://theintercept.com/2016/05/17/new-evidence-about-the-dangers-of-monsantos-roundup/ [theintercept.com]
Independent scientists have been reporting since at least 1991 that pesticides containing glyphosate along with other ingredients were more dangerous than glyphosate on its own. More recently, two papers — one published in 2002, the other in 2004 — showed that Roundup and other glyphosate-containing weed formulations were more likely to cause cell-cycle dysregulation, a hallmark of cancer, than glyphosate alone. In 2005, researchers showed that Roundup was more harmful to rats’ livers than its “active ingredient” by itself. And a 2009 study showed that four formulations of Roundup were more toxic to human umbilical, embryonic, and placental cells than glyphosate by itself.
https://www.scientificamerican.com/article/weed-whacking-herbicide-p/ [scientificamerican.com]
Until now, most health studies have focused on the safety of glyphosate, rather than the mixture of ingredients found in Roundup. But in the new study, scientists found that Roundup’s inert ingredients amplified the toxic effect on human cells—even at concentrations much more diluted than those used on farms and lawns.
One specific inert ingredient, polyethoxylated tallowamine, or POEA, was more deadly to human embryonic, placental and umbilical cord cells than the herbicide itself – a finding the researchers call “astonishing.”
“This clearly confirms that the [inert ingredients] in Roundup formulations are not inert,” wrote the study authors
See also: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955666/ [nih.gov]