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An fMRI study has found evidence of a reduction in depressive symptoms after treatment with psilocybin:
A hallucinogen found in magic mushrooms can "reset" the brains of people with untreatable depression, raising hopes of a future treatment, scans suggest.
The small study gave 19 patients a single dose of the psychedelic ingredient psilocybin. Half of patients ceased to be depressed and experienced changes in their brain activity that lasted about five weeks.
However, the team at Imperial College London says people should not self-medicate.
There has been a series of small studies suggesting psilocybin could have a role in depression by acting as a "lubricant for the mind" that allows people to escape a cycle of depressive symptoms. But the precise impact it might be having on brain activity was not known.
Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms (open, DOI: 10.1038/s41598-017-13282-7) (DX)
(Score: 1, Informative) by Anonymous Coward on Sunday October 15 2017, @06:17AM
Use a $30 food dehydrator to get the shrooms to cracker dry. It should take at least 6 hours. There are cheaper methods but this is the best and easiest. Store the dried mushrooms in an airtight container with a silicone gasket. You can add silica gel pillow packs which are a desiccant to keep it drier inside. If you buy these, make sure they are "rechargeable" aka can be heated in an oven at a low temperature to dry them.
If you don't like the taste of mushrooms, you can put them in empty gelatin pill capsules. Use a dedicated coffee grinder to make a powder from the dried mushrooms. Use a quarter or 1/8 teaspoon to scoop up powder, and push the big end of the pill from the top to force powder in. Repeat until packed. I find that I can fit 0.2 grams of powdered shrooms in a "0" size pill [capsuleconnection.com] this way. Store these pills in another airtight container with desiccant if you aren't immediately using them.