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posted by cmn32480 on Tuesday October 24 2017, @07:57PM   Printer-friendly
from the just-another-reason-to-not-be-obese dept.

Submitted via IRC for TheMightyBuzzard

Obesity leads to the release of cytokines into the bloodstream which impact the metabolism of breast cancer cells, making them more aggressive as a result. Scientists from Helmholtz Zentrum München, Technical University of Munich (TUM), and Heidelberg University Hospital report on this in 'Cell Metabolism'. The team has already been able to halt this mechanism with an antibody treatment.

The number of people with obesity is increasing rapidly worldwide. The German Cancer Research Center (DKFZ) recently reported that according to the WHO the number of children and adolescents with obesity increased tenfold between 1975 and 2016. Severe overweight can lead to various health impairments. Besides inducing cardiovascular diseases, obesity for example also promotes the development of cancer and metastases.

The current study elucidates an as yet unknown mechanism making breast cancer more aggressive. The enzyme ACC1* plays a central role in this process," said Dr. Mauricio Berriel Diaz, deputy director of the Institute for Diabetes and Cancer (IDC) at Helmholtz Zentrum München. He led the study together with Stephan Herzig, director of the IDC and professor for Molecular Metabolic Control at TUM and Heidelberg University Hospital. "ACC1 is a key component of fatty acid synthesis," said Berriel Diaz. "However, its function is impaired by the cytokines leptin and TGF-β." The levels of these cytokines are increased particularly in the blood of severely overweight subjects.

Source: https://www.helmholtz-muenchen.de/en/news/latest-news/press-information-news/article/42901/index.html


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  • (Score: 2, Insightful) by Anonymous Coward on Tuesday October 24 2017, @09:38PM (2 children)

    by Anonymous Coward on Tuesday October 24 2017, @09:38PM (#587113)

    Haha, you realize you're the massively entitled one right? You want all the benefits of public services without any of the personal costs. Moron.

    I guess you've just spent too much of your life focused on the problems in society and have developed your personality around them. Lots of people suffer from the same thing, but it helps to remind yourself that 90% of people are generally decent and good. If you don't believe that statistic then you have strayed WAY too far into cynicism and should just be ignored.

    Communities don't survive on individualism for a wide range of reasons. Maybe one day we'll be technologically advanced enough where anyone can fly off and mine some asteroids or build their own colony somewhere. That day is not now, and unless you enjoy being China / Russia's little bitch country then we're stuck in non-voluntary nations.

    Oh right, you don't propose total individualism, you want society restructured into "contracts". You're like someone who responds on Yahoo! Answers.

    Wh-wherever you find people with heads up their asses, someone wants a piece of your grandpa. And a lot of versions of me on different timelines had the same problem. So a few thousand versions of me had the [yells] INGENIOUS IDEA OF BANDING TOGETHER like a herd of cattle or a school of fish, or... those people who answer questions on Yahoo! Answers.

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  • (Score: 0) by Anonymous Coward on Tuesday October 24 2017, @09:46PM (1 child)

    by Anonymous Coward on Tuesday October 24 2017, @09:46PM (#587120)

    There's no basis for your comment.

    • (Score: 0) by Anonymous Coward on Tuesday October 24 2017, @10:00PM

      by Anonymous Coward on Tuesday October 24 2017, @10:00PM (#587131)

      Nice projection from the AC who can't muster up actual arguments to obvious problems.

      If you're trolling then you're doing a pretty damn good job at remaining serious and sticking to your script!