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posted by cmn32480 on Tuesday October 24 2017, @07:57PM   Printer-friendly
from the just-another-reason-to-not-be-obese dept.

Submitted via IRC for TheMightyBuzzard

Obesity leads to the release of cytokines into the bloodstream which impact the metabolism of breast cancer cells, making them more aggressive as a result. Scientists from Helmholtz Zentrum München, Technical University of Munich (TUM), and Heidelberg University Hospital report on this in 'Cell Metabolism'. The team has already been able to halt this mechanism with an antibody treatment.

The number of people with obesity is increasing rapidly worldwide. The German Cancer Research Center (DKFZ) recently reported that according to the WHO the number of children and adolescents with obesity increased tenfold between 1975 and 2016. Severe overweight can lead to various health impairments. Besides inducing cardiovascular diseases, obesity for example also promotes the development of cancer and metastases.

The current study elucidates an as yet unknown mechanism making breast cancer more aggressive. The enzyme ACC1* plays a central role in this process," said Dr. Mauricio Berriel Diaz, deputy director of the Institute for Diabetes and Cancer (IDC) at Helmholtz Zentrum München. He led the study together with Stephan Herzig, director of the IDC and professor for Molecular Metabolic Control at TUM and Heidelberg University Hospital. "ACC1 is a key component of fatty acid synthesis," said Berriel Diaz. "However, its function is impaired by the cytokines leptin and TGF-β." The levels of these cytokines are increased particularly in the blood of severely overweight subjects.

Source: https://www.helmholtz-muenchen.de/en/news/latest-news/press-information-news/article/42901/index.html


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  • (Score: 0) by Anonymous Coward on Tuesday October 24 2017, @09:57PM (2 children)

    by Anonymous Coward on Tuesday October 24 2017, @09:57PM (#587128)
    • Rational: Realize that few people are capable of knowing everything and thus society should help. Authoritarian measures are sometimes required such as seatbelt laws. Libertarian methods are sometimes preferred such as doing fuck-all and spending no money on a problem, or by increasing costs such as the grocery bag tax.

    Rational encompasses all the methods of governance and applies them *hopefully* where they are best suited. PS: charging people more is not very libertarian, it is a small step down from authoritarian where the choice is 100% removed. Many people were up in arms about the bag tax, but really they were paying for the bags all the time as hidden costs of their groceries. People are not generally capable of running a full fledged society all by themselves, there is a reason why we need each other. The sum is totally greater than the parts, otherwise we'd still be building houses out of branches and leaves.

  • (Score: 0) by Anonymous Coward on Tuesday October 24 2017, @10:02PM (1 child)

    by Anonymous Coward on Tuesday October 24 2017, @10:02PM (#587133)
    • I wear a seatbelt because I don't want to die, not because some bureaucrat mandates it.

    • Because of the mandates, seatbelts have remained pretty stupid in design.

    • You're implying that without mandates, no safety mechanism would have ever been adopted. What tosh.

    • (Score: 0) by Anonymous Coward on Tuesday October 24 2017, @10:08PM

      by Anonymous Coward on Tuesday October 24 2017, @10:08PM (#587137)

      Go have sex with your strawman, it seems to get you off.