SoylentNews is people
SoylentNews
A new approach to reducing bulging tummy fats has shown promise in laboratory trials. It combines a new way to deliver drugs, via a micro-needle patch, with drugs that are known to turn energy-storing white fat into energy-burning brown fat. This innovative approach developed by scientists from Nanyang Technological University, Singapore (NTU Singapore) reduced weight gain in mice on a high fat diet and their fat mass by more than 30 per cent over four weeks.
The new type of skin patch contains hundreds of micro-needles, each thinner than a human hair, which are loaded with the drug Beta-3 adrenergic receptor agonist or another drug called thyroid hormone T3 triiodothyronine.
When the patch is pressed into the skin for about two minutes, these micro-needles become embedded in the skin and detach from the patch, which can then be removed. As the needles degrade, the drug molecules then slowly diffuse to the energy-storing white fat underneath the skin layer, turning them into energy-burning brown fats.
Transdermal Delivery of Anti-Obesity Compounds to Subcutaneous Adipose Tissue with Polymeric Microneedle Patches (DOI: 10.1002/smtd.201700269) (DX)
(Score: 2) by takyon on Friday December 29 2017, @06:29PM (3 children)
I think the point is targeting the fat stored under the skin. And a high fat diet was chosen to quickly bloat up the mice so that the technology could be tested. It's not like eating brown sugar-Os every day will create a "sugar layer" under your skin that can simply be rinsed away with water.
[SIG] 10/28/2017: Soylent Upgrade v14 [soylentnews.org]
(Score: 2) by meustrus on Friday December 29 2017, @06:34PM (2 children)
No, eating brown sugar-Os every day will create the same fat layer under the skin, along with the rest of the obesity-related disorders like diabetes that are all commonly associated with each other these days. They'd get the mice even fatter with a High Fructose Corn Syrup drip, and then not only would they know more about interactions with the rest of the associated disorders, but it'd probably be cheaper too.
If there isn't at least one reference or primary source, it's not +1 Informative. Maybe the underused +1 Interesting?
(Score: 2) by takyon on Friday December 29 2017, @06:41PM (1 child)
So you acknowledge that I'm correct, you're nitpicking, and the microneedle patch is going to work or fail the same way no matter which diet the mice/humans are on?
[SIG] 10/28/2017: Soylent Upgrade v14 [soylentnews.org]
(Score: 2) by meustrus on Friday December 29 2017, @09:05PM
I acknowledge that you can gt the mice fat on a high fat diet, but it doesn't really replicate the complex of obesity-related disorders that this is likely to be used to treat. Mainly though I object to the continued use of "high fat diet" as the preferred means of fattening test subjects, because it implies that high fat diets are the culprit for most obesity in humans when that just plainly isn't true.
If there isn't at least one reference or primary source, it's not +1 Informative. Maybe the underused +1 Interesting?