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A new approach to reducing bulging tummy fats has shown promise in laboratory trials. It combines a new way to deliver drugs, via a micro-needle patch, with drugs that are known to turn energy-storing white fat into energy-burning brown fat. This innovative approach developed by scientists from Nanyang Technological University, Singapore (NTU Singapore) reduced weight gain in mice on a high fat diet and their fat mass by more than 30 per cent over four weeks.
The new type of skin patch contains hundreds of micro-needles, each thinner than a human hair, which are loaded with the drug Beta-3 adrenergic receptor agonist or another drug called thyroid hormone T3 triiodothyronine.
When the patch is pressed into the skin for about two minutes, these micro-needles become embedded in the skin and detach from the patch, which can then be removed. As the needles degrade, the drug molecules then slowly diffuse to the energy-storing white fat underneath the skin layer, turning them into energy-burning brown fats.
Transdermal Delivery of Anti-Obesity Compounds to Subcutaneous Adipose Tissue with Polymeric Microneedle Patches (DOI: 10.1002/smtd.201700269) (DX)
(Score: 2) by meustrus on Friday December 29 2017, @09:05PM
I acknowledge that you can gt the mice fat on a high fat diet, but it doesn't really replicate the complex of obesity-related disorders that this is likely to be used to treat. Mainly though I object to the continued use of "high fat diet" as the preferred means of fattening test subjects, because it implies that high fat diets are the culprit for most obesity in humans when that just plainly isn't true.
If there isn't at least one reference or primary source, it's not +1 Informative. Maybe the underused +1 Interesting?