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Research shows that longstanding depression alters the brain -- treatment may require different approaches depending on not just the severity of the depression but also on its longevity:
Is clinical depression always the same illness, or does it change over time?
New brain imaging research from the Centre for Addiction and Mental Health (CAMH) shows that the brain alters after years of persistent depression, suggesting the need to change how we think about depression as it progresses.
The study, led by senior author Dr. Jeff Meyer of CAMH's Campbell Family Mental Health Research Institute, is published in The Lancet Psychiatry.
The research shows that people with longer periods of untreated depression, lasting more than a decade, had significantly more brain inflammation compared to those who had less than 10 years of untreated depression. In an earlier study, Dr. Meyer's team discovered the first definitive evidence of inflammation in the brain in clinical depression.
This study provides the first biological evidence for large brain changes in long-lasting depression, suggesting that it is a different stage of illness that needs different therapeutics - the same perspective taken for early and later stages of Alzheimer's disease, he says.
"Greater inflammation in the brain is a common response with degenerative brain diseases as they progress, such as with Alzheimer's disease and Parkinson´s disease," says Dr. Meyer, who also holds Canada Research Chair in the Neurochemistry of Major Depression. While depression is not considered a degenerative brain disease, the change in inflammation shows that, for those in whom depression persists, it may be progressive and not a static condition.
Over years, depression changes the brain, new study shows
Depression Can Actually Leave Long-Term Changes in Your Brain, Study Shows
More information: Elaine Setiawan et al, Association of translocator protein total distribution volume with duration of untreated major depressive disorder: a cross-sectional study, The Lancet Psychiatry (2018). DOI: 10.1016/S2215-0366(18)30048-8
(Score: 2) by Freeman on Friday March 02 2018, @04:44PM (2 children)
$60k for the marriage or $60k for the therapist? Seems like, it took an awfully long time for that therapist to get you laid, if that's all that was wrong.
Seriously though, having the wrong girlfriend is 100% worse than not having a girlfriend. I'm one of those crazy people that only ever dated their wife and have been happily married for 10+ years. It's fine to have girl friends, but it's best to only date those you'd consider marrying. I know that seems crazy to some people and that I'm perceived to be "missing out" / "stupid" / "crazy" by them, but I am glad she's the only woman I've been intimate with. ++ She's the only girl I've ever kissed.
Throughout my childhood I was hyper, happy, etc. Through most of it I was also on Tegretol. Apparently it's a mood altering drug, beyond being used to control seizures. I was taken off it just before high school and have pretty much been battling depression ever since. I don't take medication for it and have never seen a therapist. Probably should have been seeing one at the start, but that's water under the bridge. I've learned to cope with depression and ADHD. Life's crazy, but you just gotta hang in there.
Back to the marriage thing. Marriage takes work and commitment from both parties. Anyone who tells you different has drunk their own koolaid.
Joshua 1:9 "Be strong and of a good courage; be not afraid, neither be thou dismayed: for the Lord thy God is with thee"
(Score: 2) by MichaelDavidCrawford on Friday March 02 2018, @05:43PM
It no longer difficult to get laid but I don't want that anymore. To the extent I seek release I really do prefer anonymous hookups with men at porn theaters or bathhouses
There are two women that I'm interested in. One has a steady boyfriend so I'm not going to wait around for her
The other I don't know her situation but I do know she's always happy to see me. I'm going to bring her some flowers next time I see her
Yes I Have No Bananas. [gofundme.com]
(Score: 2) by MichaelDavidCrawford on Friday March 02 2018, @05:55PM
Most epilepsy drugs have also been found to help manic depressives
I take Trileptal. It's very similar to Tegretol
Yes I Have No Bananas. [gofundme.com]