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posted by janrinok on Monday March 19 2018, @01:14AM   Printer-friendly
from the darwinism-ftw dept.

People's willingness to use a Zika vaccine when it's available will be influenced by how they weigh the risks associated with the disease and the vaccine, but also by their misconceptions about other vaccines, a new study has found.

While a Zika vaccine is in development, the study by researchers at the Annenberg Public Policy Center (APPC) of the University of Pennsylvania examined factors that will affect the eventual acceptance or rejection of such a vaccine.

The study, published in the Journal of Public Health, found that people's erroneous beliefs about an association between the measles, mumps, and rubella (MMR) vaccine and autism were a predictor of people's lessened intention to get a Zika vaccine. The study also found that people's perceptions of the severity of the Zika virus as well as their general belief in the power of science to solve problems increased their intention to get the vaccine.

"When a new disease arises, people who lack understanding of the new threat may extrapolate from their knowledge of other diseases," said Yotam Ophir, a Ph.D. candidate at Penn's Annenberg School for Communication who co-authored the study with APPC Director Kathleen Hall Jamieson. "We found that the misbelief about the MMR vaccine's association with autism was more influential on the decision of whether to get vaccinated for Zika than even perceptions of Zika itself, which is worrisome, especially in light of the persistence of that misinformation."

[...] The bogus association between the MMR vaccine and autism has been disproven in numerous studies. However, the argument is still prominent among people who oppose vaccinations. "Scientists often look at the effect of misinformed beliefs about the MMR vaccine on people's intention to vaccinate children with the triple vaccine, but they don't as often look at the dangerous spillover effects that these misbeliefs can have," said Ophir, who will be joining APPC as a postdoctoral fellow.

He said that prior research has shown that it is very hard to completely debunk misinformation, such as the mistaken belief that the MMR vaccine causes autism, but the study results suggest that accurately communicating about the risks of Zika can help lessen the detrimental effects of the misbelief. "Even if we can't change what people think about the MMR vaccine, if we can give them an accurate picture of how vulnerable they are to a disease such as Zika, they can make a more informed decision about it," Ophir said.


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  • (Score: 4, Informative) by NotSanguine on Monday March 19 2018, @04:45AM (4 children)

    Links to "cited" data?
    Copies of FOIA requests?

    All I see here are claims unsupported by data and innuendo.

    You made statements:

    As crazy as most alternative-beliefers are, they're correct that at one point, vaccines were able to cause autism-like conditions. Completely discrediting misinformation, just makes it more prevalent and creates more "anti-sciencers" (the same thing happened with the left-of-center groups against the right-of-center groups during the elections, see: Clinton's "deplorables"). At this point, it would make more sense to acknowledge that it did happen, and the the CDC + FDA are more liberal (the word for lenient, not the political associations) in their green-lighting of medical formulations. Some would say almost dangerously heedless, to which I would agree.

    The first is unsupported by any data I've seen (this is not said data, but gives a good overview: https://en.wikipedia.org/wiki/MMR_vaccine#Safety). [wikipedia.org]

    The second is irrelevant to the discussion at hand and, I'd like to see the data for myself, rather than taking your word for it.

    What's more, your characterization of the FDA's testing methods do have some factual basis, in that the drug studies submitted for drug approval are, in fact, done by the manufacturers themselves. What's more, the review process for those studies, while performed in-house by the FDA, are generally underwritten by those manufacturers.

    That's not some big secret, nor has it, AFAICT, generally had a negative effect (as you imply) on the safety of approved drugs.

    In fact, while there have certainly been issues with that process at times, they have proven, with few exceptions, remarkably robust WRT safety.

    I'm not sure what bug you have up your ass about the FDA and CDC, but your misrepresentations cause me to think you're some sort of crank.

    So let's see that data (links to the DB's you mention would be a good start) and the "runaround" with respect to the "FOIA requests" you claim to have filed.

    Until then, I stand by my initial assessment: You're talking out of your ass and it smells that way too.

    --
    No, no, you're not thinking; you're just being logical. --Niels Bohr
    Starting Score:    1  point
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    Total Score:   4  
  • (Score: 0, Troll) by cocaine overdose on Monday March 19 2018, @05:43AM (3 children)

    >Links to "cited" data?

    Point me to the data you want. Specifics, see my last point "I will be more than happy to provide the sources for any of these, but please make your request coherent and specific. I will not track down "every single study on amphetamine's bioequivalence.""

    >FOIA copy

    Absolutely not.

    >https://en.wikipedia.org/wiki/MMR_vaccine#Safety).

    This is not a source. This is a lazy umbrella for independent research and I won't read through it all. For autism-to-thimersol analysis, see the other research I posted: [PMID: 24354891]

    >The second is irrelevant to the discussion at hand and, I'd like to see the data for myself, rather than taking your word for it.

    Again, see #1.

    >That's not some big secret, nor has it, AFAICT, generally had a negative effect (as you imply) on the safety of approved drugs.

    Observations: 1A, 1B, 1E, 2C (specifically related to particle excursions -- these are the negative effects under Observation 2), 3A, 5D, 9A, 9B[1] -- for reported complaints. The rest will be harder to find, because the FDA does not report manufacturer in its incidence reports.

    >In fact, while there have certainly been issues with that process at times, they have proven, with few exceptions, remarkably robust WRT safety.

    Are you using WRT in some uncommon fashion? It's not applicable to anything we discussed, and as always, sources required for your claim that the FDA process is proven, and with few exceptions, robust towards safety. A lack of contrary evidence is not evidence.

    As for the rest, make your requests succinct. As much as I would like to educate you on this topic, I am not so devoid of things to do that I would hunt down and compend an encyclopaedia for yours.

    [1]https://www.fda.gov/downloads/AboutFDA/CentersOffices/OfficeofGlobalRegulatoryOperationsandPolicy/ORA/ORAElectronicReadingRoom/UCM552668.pdf
    • (Score: 2) by NotSanguine on Monday March 19 2018, @06:22AM (1 child)

      Point me to the data you want. Specifics, see my last point "I will be more than happy to provide the sources for any of these, but please make your request coherent and specific. I will not track down "every single study on amphetamine's bioequivalence.""

      You provide a reference to a paywalled paper [sciencedirect.com] (which, given the state of scientific publishing isn't surprising), and the abstract is vague in the extreme. As such, I can't make much of what's there. Especially since other paywalled papers [sciencedirect.com] directly contradict the conclusions of the one you referenced.

      Sadly, I have no access to either paper or the data upon which they were based. Do you? Care to share?

      You also provide a link (https://www.fda.gov/downloads/AboutFDA/CentersOffices/OfficeofGlobalRegulatoryOperationsandPolicy/ORA/ORAElectronicReadingRoom/UCM552668.pdf) to site reports concerning a single manufacturer's operational issues. Where are all the others you've cited? I think the number was 55? And there's no reference to any actions that the FDA may or may not have taken in response to those (or any other issues). Shall I just take your word for it that no fines or other sanctions were levied?

      I'd also point out that we're discussing the MMR vaccine, not amphetamines here, although there seemed to be compounds other than amphetamines (at least in my cursory scan through the poorly copied PDF) that were primarily at issue.

      I'm sure you believe what you're going on about. And good for you! All the same, you haven't provided any factual support for your claims. Just disputed claims and a single, marginally relevant report which doesn't provide factual evidence of your claims.

      Whatever. Carry on.

      --
      No, no, you're not thinking; you're just being logical. --Niels Bohr
      • (Score: 0, Troll) by cocaine overdose on Monday March 19 2018, @06:46AM

        >You provide a reference to a paywalled paper [sciencedirect.com] (which, given the state of scientific publishing isn't surprising), and the abstract is vague in the extreme. As such, I can't make much of what's there. Especially since other paywalled papers [sciencedirect.com] directly contradict the conclusions of the one you referenced.

        My god man, what year is it? Let Me Sci-Hub That For You. I'm also very confused how you ended up at ScienceDirect from a PubMed number. https://link.springer.com/content/pdf/10.1186%2F2047-9158-2-25.pdf

        >Where are all the others you've cited? I think the number was 55?

        A one https://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/CDERFOIAElectronicReadingRoom/UCM556141.pdf A two https://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/CDERFOIAElectronicReadingRoom/UCM556141.pdf A three https://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/CDERFOIAElectronicReadingRoom/UCM577372.pdf And a four https://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/CDERFOIAElectronicReadingRoom/UCM557175.pdf

        As for the 55, search https://www.fda.gov/ICECI/Inspections/ucm346077.htm for all references of "Auro."

        >And there's no reference to any actions that the FDA may or may not have taken in response to those (or any other issues). Shall I just take your word for it that no fines or other sanctions were levied?

        A bingo https://www.fda.gov/ICECI/Inspections/ucm256377.htm , a bongo https://www.fda.gov/RegulatoryInformation/LawsEnforcedbyFDA/default.htm , and a bango https://www.fda.gov/ICECI/EnforcementActions/WarningLetters/default.htm . And for the really skeptical, a killamanjaro: https://www.fda.gov/AboutFDA/WhatWeDo/

        The basic point connecting these four documents, straight from the horses mouth, is that the FDA doesn't enforce anything in the generics department. Read those very short excepts, and tell me what you believe the FDA would do if AuroBindo started putting arsenic in their generics.

        >I'd also point out that we're discussing the MMR vaccine, not amphetamines here, although there seemed to be compounds other than amphetamines (at least in my cursory scan through the poorly copied PDF) that were primarily at issue.

        My main man, my macho nacho, my triskilin taint, you are the one that keeps veering off course. Let me remind you of how we got here in the first place! I made a post laying out all the info I had, this is colloquially referred to as the "opening post." And in this post I voiced my complaints about the FDA. But wait, you egged your humble educator on, to provide more evidence of histh claims, and how he did! Yet, your responses, when met with data you cannot refute, has been to switch subjects! My, how the stubborn have fallen! Well, enough making jokes of you, fellow. AuroBindo is a manufacturer that produces generic amphetamines. In the same plants they produce generic amphetamines, they produce other generics! Very rivetting stuff, I know I know. However, these processees are not separate. One worker pissing in the batch of grandma's fentanyl, does not mean another will not take a dump in my precious amphetamines. In lay terms, if he's gone ahead and stolen your car, you best bet he took your keys too.

        >Whatever. Carry on.

        Tch tch tch. I see your energy has faded, once you've been met with some real resistance in you life, eh fellow? No matter, after a quick nap and a quick fap (which unfortunately with the state of today's pornos could not be "finished"), I am revitalized. Come, fellow, en garde. You fired your flintlock towards my head, and now you run like a coward when you spilled your gunpowder. Face me like a man, man!
    • (Score: 2) by NotSanguine on Monday March 19 2018, @06:22AM

      Point me to the data you want. Specifics, see my last point "I will be more than happy to provide the sources for any of these, but please make your request coherent and specific. I will not track down "every single study on amphetamine's bioequivalence.""

      You provide a reference to a paywalled paper [sciencedirect.com] (which, given the state of scientific publishing isn't surprising), and the abstract is vague in the extreme. As such, I can't make much of what's there. Especially since other paywalled papers [sciencedirect.com] directly contradict the conclusions of the one you referenced.

      Sadly, I have no access to either paper or the data upon which they were based. Do you? Care to share?

      You also provide a link (https://www.fda.gov/downloads/AboutFDA/CentersOffices/OfficeofGlobalRegulatoryOperationsandPolicy/ORA/ORAElectronicReadingRoom/UCM552668.pdf) to site reports concerning a single manufacturer's operational issues. Where are all the others you've cited? I think the number was 55? And there's no reference to any actions that the FDA may or may not have taken in response to those (or any other issues). Shall I just take your word for it that no fines or other sanctions were levied?

      I'd also point out that we're discussing the MMR vaccine, not amphetamines here, although there seemed to be compounds other than amphetamines (at least in my cursory scan through the poorly copied PDF) that were primarily at issue.

      I'm sure you believe what you're going on about. And good for you! All the same, you haven't provided any factual support for your claims. Just disputed claims and a single, marginally relevant report which doesn't provide factual evidence of your claims.

      Whatever. Carry on.

      --
      No, no, you're not thinking; you're just being logical. --Niels Bohr