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posted by janrinok on Saturday March 24 2018, @11:31AM   Printer-friendly
from the is-there-anything-that-stem-cells-cannot-do? dept.

Stem cell therapy may help reverse effects of premature menopause, restore fertility

Young women with premature ovarian insufficiency (POI) may be able to use their own bone marrow stem cells to rejuvenate their ovaries and avoid the effects of premature menopause, new research suggests. The preliminary results from the ongoing ROSE clinical trial will be presented Tuesday at ENDO 2018, the 100th annual meeting of the Endocrine Society, in Chicago, Ill.

"In the two participants who have completed the treatment to date, serum estrogen levels have increased as soon as 3 months after the injection of stem cells, and the effect has lasted for at least one year. Their menopausal symptoms have been alleviated, and six months after the injection of the stem cells into the ovaries, they have resumed menses," said senior author Ayman Al-Hendy, M.D., Ph.D., Professor of Gynecology and Director of Translational Research at the University of Illinois at Chicago.

The researchers plan to enroll 33 participants in their clinical trial. For the two patients who have undergone the procedure so far, they collected each woman's own mesenchymal stem cells from her posterior iliac crest bone marrow and used minimally invasive laparoscopy to inject the cells into one ovary, keeping the second, untreated, ovary as a control. The authors followed the patients closely with frequent blood work, imaging of the ovaries, menopausal symptom questionnaires, and safety studies.

Now that both women's estrogen levels have increased significantly and they have begun to menstruate, the research team looks forward to the possibility that they may again become fertile.

ENDO 2018. Because #IAmEndocrinology.


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  • (Score: 0) by Anonymous Coward on Saturday March 24 2018, @03:39PM (2 children)

    by Anonymous Coward on Saturday March 24 2018, @03:39PM (#657552)

    Does the world need *even more* fertility of the human race? Really?

    If you're spending that money because research is important, and knowledge is cool, than keep right going. (honestly, not sarcastically)

    But: 1% of women have early menopause. Approx. 5% have it for a reason that is targeted by this study. 50% (my guess) are suffering from it (whereas the other 50% don't care, already having had all the kids they want; this is a personal guess).

    So if you're spending money, time and brainpower to improve the *fertility* of 0,025% of women, THEN MOVE YOUR FUCKING ASS AND DO SOMETHING USEFUL FOR A CHANGE!! Malaria, pretty much all cancers, Alzheimer's, Parkinson's, and also the GODDAMN OVERPOPULATION PROBLEM (aka male birth control) are waiting for you! Asshole!

  • (Score: 0) by Anonymous Coward on Saturday March 24 2018, @09:19PM

    by Anonymous Coward on Saturday March 24 2018, @09:19PM (#657671)

    I'm not sure that I agree with your upsetness.
    you have an easy solution: stop paying the people who don't research what you want them to research.
    if you weren't paying them in the first place, then there's a slightly not easy solution: start talking to people, initiate and get legislation passed that will increase the taxes on those people who ARE funding research you think is unimportant, and then use those taxes to pay or the research you want.

  • (Score: 0) by Anonymous Coward on Saturday March 24 2018, @10:53PM

    by Anonymous Coward on Saturday March 24 2018, @10:53PM (#657695)

    It might need more fertility for the next race.