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posted by Fnord666 on Tuesday March 27 2018, @09:09PM   Printer-friendly
from the feeling-salty dept.

One of the key steps in developing new drugs is determining the atomic structure of its biologically active substances. This generally involves performing X-ray analyses of single crystal structures to determine the ingredient's detailed three-dimensional set-up. However, growing suitable single crystals is often a complex and time-consuming process.

A research group headed up by Bernhard Spingler, professor at the Department of Chemistry of the University of Zurich, has now modified a method that had previously been used exclusively for the crystallization of proteins, and successfully applied it to organic salts. The team was able to determine the crystal structures of several organic salts with significantly less time and effort. "As organic salts make up about 40 percent of all active pharmaceutical ingredients, this new method can greatly speed up the development of drugs," says Spingler.

[...] The breakthrough in developing the novel method was achieved by Philipp Nievergelt, a trainee who had spent 10 months in Bernhard Spingler's lab after graduating from Gymnasium. The successful junior researcher is listed as first author of the study and is now four semesters into his business chemistry studies at UZH. "The traineeship got me excited about lab work and encouraged me to continue doing research," explains Nievergelt.


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  • (Score: 2) by ilPapa on Wednesday March 28 2018, @03:13AM (1 child)

    by ilPapa (2366) on Wednesday March 28 2018, @03:13AM (#659319) Journal

    four semesters into his business chemistry studies

    I'm not sure what is taught in "business chemistry studies", but I'm thinking they should either find a new name or just enroll all their students - immediately - into an ethics course.

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  • (Score: 0) by Anonymous Coward on Wednesday March 28 2018, @06:42PM

    by Anonymous Coward on Wednesday March 28 2018, @06:42PM (#659625)

    drugs developpement d'uh