Stories
Slash Boxes
Comments

SoylentNews is people

posted by martyb on Wednesday April 04 2018, @03:10PM   Printer-friendly
from the Science-at-work dept.

A disputed paper that raised questions about the safety of CRISPR has been retracted:

A scientific paper that purported to lay bare serious flaws in the gene-editing tool known as CRISPR and briefly tanked shares of genome-editing companies has been retracted by its publisher.

The paper [DOI: 10.1038/nmeth.4293] [DX], published last year in Nature Methods, claimed that CRISPR wreaked havoc on the genome, causing hundreds of unintended mutations in mice — and that the algorithms typically used to detect these changes were routinely missing them.

[...] Two months after publication of the paper, Nature Methods published an "an expression of concern" about the paper in July. The retraction notice, appended Friday, goes further, saying the authors did not use mice that had been bred in their own laboratory — so they could not know if any genetic mutations were the result of their intervention with CRISPR editing, or if it stemmed from variations in the mice's own genomes.

Nature Methods editorial discussing the retraction: CRISPR off-targets: a reassessment (open, DOI: 10.1038/nmeth.4664) (DX)

Previously: CRISPR Safer than Thought; Misleading Study Found Shared Mutations in Closely Related Mice


Original Submission

 
This discussion has been archived. No new comments can be posted.
Display Options Threshold/Breakthrough Mark All as Read Mark All as Unread
The Fine Print: The following comments are owned by whoever posted them. We are not responsible for them in any way.
  • (Score: 2) by Gaaark on Wednesday April 04 2018, @04:20PM (5 children)

    by Gaaark (41) on Wednesday April 04 2018, @04:20PM (#662537) Journal

    so many of society's ills can be traced back to a particular cause: Large swaths of the population who have an IQ less than 85.

    REEEally... i didn't know that Trump and Hillary and the rest of the 'leaders', and soooo many of the rich had such a low IQ!
    Innnnnteresting.

    So, with CRISPR, we could raise all their IQ's and make them better, more productive beings?

    We can rebuild them? Make them smarter, smarter, smarter?
    We can make Hillary the next 6 million dollar man!?!

    --
    --- Please remind me if I haven't been civil to you: I'm channeling MDC. ---Gaaark 2.0 ---
    Starting Score:    1  point
    Karma-Bonus Modifier   +1  

    Total Score:   2  
  • (Score: 0) by Anonymous Coward on Wednesday April 04 2018, @04:23PM

    by Anonymous Coward on Wednesday April 04 2018, @04:23PM (#662538)

    There are somatic differences in both brain structure and efficiency, which might therefore require early intervention to ensure the development of full potential.

  • (Score: 2) by maxwell demon on Wednesday April 04 2018, @05:15PM (2 children)

    by maxwell demon (1608) on Wednesday April 04 2018, @05:15PM (#662558) Journal

    So, with CRISPR, we could raise all their IQ's

    No. Since the average is by definition always 100, you'll reduce every other's IQ that way. Mensa would lose quite a few members! ;-)

    --
    The Tao of math: The numbers you can count are not the real numbers.
    • (Score: 0) by Anonymous Coward on Wednesday April 04 2018, @05:52PM (1 child)

      by Anonymous Coward on Wednesday April 04 2018, @05:52PM (#662568)

      Reminds me of microcephaly (https://en.wikipedia.org/wiki/Microcephaly), by definition it can never be cured. Actually when everyone is exactly the same they will all be diagnosed with it.

      • (Score: 2) by Gaaark on Wednesday April 04 2018, @06:41PM

        by Gaaark (41) on Wednesday April 04 2018, @06:41PM (#662581) Journal

        PINHEADS!
        One of us!
        One of us!
        One of us!

        --
        --- Please remind me if I haven't been civil to you: I'm channeling MDC. ---Gaaark 2.0 ---
  • (Score: 0) by Anonymous Coward on Wednesday April 04 2018, @10:18PM

    by Anonymous Coward on Wednesday April 04 2018, @10:18PM (#662664)

    > We can make Hillary the next 6 million dollar man!?!

    Indeed. It's the only thing that could get her elected!