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posted by martyb on Wednesday April 04 2018, @03:10PM   Printer-friendly
from the Science-at-work dept.

A disputed paper that raised questions about the safety of CRISPR has been retracted:

A scientific paper that purported to lay bare serious flaws in the gene-editing tool known as CRISPR and briefly tanked shares of genome-editing companies has been retracted by its publisher.

The paper [DOI: 10.1038/nmeth.4293] [DX], published last year in Nature Methods, claimed that CRISPR wreaked havoc on the genome, causing hundreds of unintended mutations in mice — and that the algorithms typically used to detect these changes were routinely missing them.

[...] Two months after publication of the paper, Nature Methods published an "an expression of concern" about the paper in July. The retraction notice, appended Friday, goes further, saying the authors did not use mice that had been bred in their own laboratory — so they could not know if any genetic mutations were the result of their intervention with CRISPR editing, or if it stemmed from variations in the mice's own genomes.

Nature Methods editorial discussing the retraction: CRISPR off-targets: a reassessment (open, DOI: 10.1038/nmeth.4664) (DX)

Previously: CRISPR Safer than Thought; Misleading Study Found Shared Mutations in Closely Related Mice


Original Submission

 
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  • (Score: 0) by Anonymous Coward on Thursday April 05 2018, @11:46AM

    by Anonymous Coward on Thursday April 05 2018, @11:46AM (#662876)

    Rather, intelligence allows for higher education.