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posted by Fnord666 on Saturday April 07 2018, @02:06AM   Printer-friendly
from the give-it-away dept.

U.S. Surgeon General Jerome Adams has urged more Americans to carry the opioid overdose reversal treatment naloxone, known under brand names such as Narcan and Evzio. However, the drug and its delivery systems have become more expensive in recent years:

As opioid-related deaths have continued to climb, naloxone, a drug that can reverse overdoses, has become an important part of the public health response. When people overdosing struggle to breathe, naloxone can restore normal breathing and save their lives. But the drug has to be given quickly.

On Thursday, U.S. Surgeon General Jerome Adams issued an advisory that encouraged more people to routinely carry naloxone. "The call to action is to recognize if you're at risk," he tells Morning Edition's Rachel Martin. "And if you or a loved one are at risk, keep within reach, know how to use naloxone."

[...] The medicine is now available at retail pharmacies in most states without a prescription. Between 2013 and 2015, researchers found a tenfold increase in naloxone sold by retail pharmacies in the U.S. But prices have increased along with demand. Naloxone-filled syringes that used to cost $6 apiece now cost $30 and up. A two-pack of naloxone nasal spray can cost $135 or more. And a two-pack of automatic naloxone injectors runs more than $3,700. And while it's true that naloxone can prevent many opioid-related deaths, it doesn't solve the root cause of the problem.

Also at NYT and CNN.

Related: Kroger Supermarkets to Carry Naloxone Without a Prescription
Chicago Jail Handing Out Naloxone to Inmates Upon Release
Opioid Crisis Official; Insys Therapeutics Billionaire Founder Charged; Walgreens Stocks Narcan


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  • (Score: 5, Informative) by Booga1 on Saturday April 07 2018, @02:16AM (28 children)

    by Booga1 (6333) on Saturday April 07 2018, @02:16AM (#663614)

    Just who do they expect to buy it?
    Random people(why would they need it)? Family members of drug addicts(the same ones in denial about the whole mess)? The addicts themselves(who'd buy another hit first)?

    Then there's the aspect of needing to use it. I've heard some cops/medics get assaulted when the person comes down from the OD. They're pissed you took their high away from them!

    Though, I guess the "two pack" thing is probably good. After all, either you encounter two people OD'ing together like boyfriend and girlfriend, or you need to save someone a second time later because of a relapse.

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  • (Score: 3, Interesting) by milsorgen on Saturday April 07 2018, @02:19AM (11 children)

    by milsorgen (6225) on Saturday April 07 2018, @02:19AM (#663615)

    I'd prefer carrying rattlesnake antivenom and an EpiPen for my bee allergy. But the prices on those are insane.

    That said if things are really that bad that Americans need to carry this around then I'll carry some in the cars first aid kit if the prices were low enough.

    Fun reading: https://www.washingtonpost.com/news/wonk/wp/2015/09/09/the-crazy-reason-it-costs-14000-to-treat-a-snakebite-with-14-medicine/?utm_term=.240393c64f1c [washingtonpost.com]

    --
    On the Oregon Coast, born and raised, On the beach is where I spent most of my days...
    • (Score: 2) by takyon on Saturday April 07 2018, @02:26AM

      by takyon (881) <takyonNO@SPAMsoylentnews.org> on Saturday April 07 2018, @02:26AM (#663617) Journal
    • (Score: 1, Informative) by Anonymous Coward on Saturday April 07 2018, @02:30AM (1 child)

      by Anonymous Coward on Saturday April 07 2018, @02:30AM (#663619)

      Things aren't as bad as you think. They're worse. You wouldn't notice because you're a car owner. Try riding the bus sometime and see some real Americans who live real shitty lives.

      • (Score: 0, Funny) by Anonymous Coward on Saturday April 07 2018, @06:19AM

        by Anonymous Coward on Saturday April 07 2018, @06:19AM (#663683)

        Hey! I Ride the Bus! And I don't have a shitty life! Does take me twice as long as driving to my destination, sometimes. And there is always the risk of sitting in the recently abandoned bum-shit seat. Pays to look, and smell. But point taken, these poop-stained crazy people have the right to keep and bear arms, just like Cat-scratched Fever Pedofile Ted Nugent!!! Who crapped and pissed his own pants for a week (Guiness book? Records?) to get out of being drafted to go to Vietnam. Frenking Coward! And really, really bad guitar player. And even worse hunter, from an ethical point of view.

    • (Score: 0) by Anonymous Coward on Saturday April 07 2018, @03:18AM (2 children)

      by Anonymous Coward on Saturday April 07 2018, @03:18AM (#663638)

      According to Boyer's model, a single vial of antivenom that would cost more than $14,000 in the United States would cost $100 to $200 in Mexico. Same medicine. Same manufacturer. But a totally different pharmaceutical market.

      • (Score: 0) by Anonymous Coward on Saturday April 07 2018, @06:14AM (1 child)

        by Anonymous Coward on Saturday April 07 2018, @06:14AM (#663682)

        One of these things is not like the others! One of these things doesn't belong! One of these things is not like the others, can you tell before I finish this song?

        • (Score: 1, Interesting) by Anonymous Coward on Saturday April 07 2018, @07:26AM

          by Anonymous Coward on Saturday April 07 2018, @07:26AM (#663698)

          Legal environment.... its what happens when the Government is given authority to meddle in the market with crony capitalism.

          Its how the one percenters make money. The rest of us have other names for doing the same thing.

    • (Score: 2, Informative) by Anonymous Coward on Saturday April 07 2018, @03:25AM (3 children)

      by Anonymous Coward on Saturday April 07 2018, @03:25AM (#663641)

      A contradiction is an unemployment rate of 4.1% combined with opioid epidemic. Employment stats are crap, and the opioid epidemic is basically the 80's inner city crack epidemic metastasized to rural America.

      • (Score: 0) by Anonymous Coward on Saturday April 07 2018, @03:54AM

        by Anonymous Coward on Saturday April 07 2018, @03:54AM (#663658)

        What do you mean the employment stats are crap? Michael David Crawford is employed in software development, and he's a mentally ill old bald white man. If a mentally ill old bald white man can find a tech job, we must be at full employment!

      • (Score: 3, Informative) by Anonymous Coward on Saturday April 07 2018, @03:56AM (1 child)

        by Anonymous Coward on Saturday April 07 2018, @03:56AM (#663659)

        Normally, that would be a contradiction, but a huge number of the people abusing opiods are people that got hooked following medical treatment. They were given painkillers that they may not have needed and were not given an adequate treatment plan to get them off the junk when they were no longer in need. To make matters worse, in much of the US doctors can't prescribe medical marijuana that doesn't carry the same risks that opiods do.

        The result is that you've got this unusual group of addicts that didn't start due to having issues, they started because their doctors got them hooked.

        And as long as we treat this like it's a personal failing and not a societal health crisis, we're going to see the bodies continue to pile up as people judge the addicts and treat them as pariahs.

        • (Score: 0) by Anonymous Coward on Sunday April 08 2018, @05:31PM

          by Anonymous Coward on Sunday April 08 2018, @05:31PM (#663999)

          And some of it is because of stuff like this:
          http://www.latimes.com/projects/oxycontin-part1/ [latimes.com]

          But OxyContin’s stunning success masked a fundamental problem: The drug wears off hours early in many people, a Los Angeles Times investigation found. OxyContin is a chemical cousin of heroin, and when it doesn’t last, patients can experience excruciating symptoms of withdrawal, including an intense craving for the drug.

          Purdue has known about the problem for decades. Even before OxyContin went on the market, clinical trials showed many patients weren’t getting 12 hours of relief. Since the drug’s debut in 1996, the company has been confronted with additional evidence, including complaints from doctors, reports from its own sales reps and independent research.
                  The company has held fast to the claim of 12-hour relief, in part to protect its revenue. OxyContin’s market dominance and its high price — up to hundreds of dollars per bottle — hinge on its 12-hour duration. Without that, it offers little advantage over less expensive painkillers.
                  When many doctors began prescribing OxyContin at shorter intervals in the late 1990s, Purdue executives mobilized hundreds of sales reps to “refocus” physicians on 12-hour dosing. Anything shorter “needs to be nipped in the bud. NOW!!” one manager wrote to her staff.
                  Purdue tells doctors to prescribe stronger doses, not more frequent ones, when patients complain that OxyContin doesn’t last 12 hours. That approach creates risks of its own. Research shows that the more potent the dose of an opioid such as OxyContin, the greater the possibility of overdose and death.
                  More than half of long-term OxyContin users are on doses that public health officials consider dangerously high, according to an analysis of nationwide prescription data conducted for The Times.

          Your country is rather fucked up if you really need so many people carrying naloxone around. And if it is that fucked up one of your priorities should be jailing those responsible so stuff like this is less likely to happen.

    • (Score: 2) by MichaelDavidCrawford on Saturday April 07 2018, @07:02AM

      by MichaelDavidCrawford (2339) Subscriber Badge <mdcrawford@gmail.com> on Saturday April 07 2018, @07:02AM (#663694) Homepage Journal

      Want to meet up sometime?

      I live in Vancouver, work in Beaverton. I don't have wheels but greyhound goes to the coast.

      --
      Yes I Have No Bananas. [gofundme.com]
  • (Score: 0) by Anonymous Coward on Saturday April 07 2018, @02:40AM (1 child)

    by Anonymous Coward on Saturday April 07 2018, @02:40AM (#663622)

    Question: Can police looking to gain information use naloxone to torture people, by using it to counteract opiate painkillers given to a patient by medical staff.

    • (Score: 0) by Anonymous Coward on Saturday April 07 2018, @02:47AM

      by Anonymous Coward on Saturday April 07 2018, @02:47AM (#663624)

      Yes, and the best part is police can order medical staff to administer naloxone for them. It doesn't violate the Hippocratic Oath since causing pain isn't strictly the same as causing harm. Any doctor who refuses can be arrested and have their medical license revoked.

  • (Score: 5, Informative) by All Your Lawn Are Belong To Us on Saturday April 07 2018, @03:04AM (1 child)

    by All Your Lawn Are Belong To Us (6553) on Saturday April 07 2018, @03:04AM (#663630) Journal

    On using it and possibly encountering violence: True. The addict doesn't recognize that they were in a condition where brain damage or death is possible. They don't always come to lucidly (a function of how much opioid to how much naloxone you've pushed) and may strike out at anyone. Projectile vomit is also a possibility and one should be prepared to clear choke - aspirating on vomit can make the situation worse. But ahead of emesis is Rule #1: Always protect yourself first.

    However, yes. Family members and/or significant others are one target for this. Or a Good Samaritan, but it isn't the same as pushing aspirin for a possible heart attack.

    As to the "two pack thing," that is because the counteraction doesn't necessarily last long and one should be prepared with a second dose if necessary. In a worst-of-the-worst it can last only 5 minutes before another dose is necessary to keep someone breathing. (Well, worst-of-worst is no response...)

    The really ironic part.... in my jurisdiction cops can carry and use it as first responders (EMR). Paramedics can. Now family members will be able to. But EMT-Basics? Nope.

    --
    This sig for rent.
  • (Score: 5, Informative) by JoeMerchant on Saturday April 07 2018, @03:05AM (11 children)

    by JoeMerchant (3937) on Saturday April 07 2018, @03:05AM (#663631)

    Just who do they expect to buy it?
    Random people (why would they need it)?

    Yes, because this PSA is brought to you by the Naloxone lobbyists.

    Family members of drug addicts(the same ones in denial about the whole mess)?

    Especially them, not every family or close friend is in Red-state denial. I know a recovered addict and during his recovery process he couldn't get enough of the synthetic wean-down drug. His father flew out to Seattle to help him: a) taper off as quickly as possible and b) score some H on the street for when the pharmacy wasn't supplying enough. With his dad's support he sort-of kicked it within 6 months, moved away from Seattle, and about 5 years later he got clean for good - and not dead, bonus.

    The addicts themselves(who'd buy another hit first)?

    Again, with the right kind of support the addicts would carry Naloxone, though you're right about what they'd choose for themselves.

    Naloxone-filled syringes that used to cost $6 apiece now cost $30 and up.

    And this is an even bigger problem for the addicts, because it's getting expensive enough that they can trade theirs for a score...

    But, in our great Capitalist state, demand is up - why would the manufacturer do anything to bring the price down? Keep it high for a good long time, then ramp up supply to grab as much money from the market as they can, it's a well studied science of monopoly controlled supply/demand/price relationships.

    --
    🌻🌻 [google.com]
    • (Score: 2) by takyon on Saturday April 07 2018, @03:09AM (7 children)

      by takyon (881) <takyonNO@SPAMsoylentnews.org> on Saturday April 07 2018, @03:09AM (#663634) Journal

      The patent on naloxone is expired. But that doesn't help Americans.

      --
      [SIG] 10/28/2017: Soylent Upgrade v14 [soylentnews.org]
      • (Score: 2) by JoeMerchant on Saturday April 07 2018, @03:15AM (5 children)

        by JoeMerchant (3937) on Saturday April 07 2018, @03:15AM (#663636)

        The patent on naloxone is expired.

        That will only matter when a non-carpetbagger manufacturer enters the picture and starts to bring the prices down.

        --
        🌻🌻 [google.com]
      • (Score: 3, Interesting) by Hyperturtle on Saturday April 07 2018, @04:15PM

        by Hyperturtle (2824) on Saturday April 07 2018, @04:15PM (#663751)

        It's too late for me to go back and reply to comments about the FDA's concern about bacteria and a marketing campaign shortly afterwards, but how many days was it this time between that announcement and this next one? On March 22nd 1990 tryptophan was banned; on March 26th Prozac was promimently announced in Newsweek (it had been available since 1987 or so, but it wasn't "popular" yet, and had been struggling). I'd summarized that in my post and suggested the first shot had been fired.

        Similarly, naxlone has been available for a while, but the prices have gone up and it's somewhat morbid to have such a specific antidote for what used to be a fringe problem not caused by the actual industry selling the problem itself. It 's also expensive to just stock up in case someone, anyone, should need it.

        So, how long did it take for a promiment person, place or thing to make the announcement to buy something else?

        It took them 2 Days. April 3rd was the announcement they were going after Triangle Pharmanaturals due to the bacteria and banning their product and seeking to shut the place down, and then on April 5th the surgeon general of the USA announced that everyone should "routinely carry naloxone." People would likely not need that, nor the present targeted uses for kratom, if perhaps they were not exploited by the drug industry to begin with.

        My post about the kratom and the predictable course of action is here.

        https://soylentnews.org/article.pl?sid=18/04/04/1142227 [soylentnews.org]

        I haven't come up with a good reply for my detractor, other than that I have a vested interest in the health of myself and others, and pay attention to health laws. I do not have to have been around the block in order to read the signs and know where the road is going to lead. We've seen these signs before.

        Being persuaded (instructed) to take an expensive product while not offering a suitable alternative is not in most people's interests, and I imagine it is only in the interests of those that profit from the expensive product.

        The entire problem would have been completely preventable if opiates were not handed out so readily to people that could have had their needs handled differently.

        Also, I am not only referring to drugs with what we can call multiple uses. I am referring to actual utilitarian stuff; I had in mind the red rice yeast powder debacle; I'm irritated I didn't mention it, so here's a wikipedia article that describes what the problem was and what the FDA did. (https://en.wikipedia.org/wiki/Red_yeast_rice)

        The Red yeast rice powders in question have a naturally occuring substance, that much to the chagrin of others, turned out to be identical to what the drug lovastin has (and lovastin cost so much to create and test as a synthetic; they were very upset to find it already existed in nature *and* was already used for the same purpose). In what may sound familiar, the FDA did the most reasonable thing we might guess they could do-- they chose to ban products containing red rice yeast, because to them it was now a drug to be controlled, despite previously it not even being on their radar.

        In that case, it affected things at first, but over time, the red rice yeast powder kept popping up and the FDA now have difficulty suppressing it. This is largely because instead of being marketed for something specific, it's another case of "don't ingest these products made specifically for ingestion" on the product packaging. They now suggest that because it's just as powerful as a drug, you really should go see a doctor and get the genuine thing because we said so." At least they couldn't get people addicted to cholestorl drugs so they could try to peddle a "cure". However, you do not sell nearly as many cholesterol lowering products at the same places one might buy other "for external use only" products, and thus it escapes the wrath of some of righteous -- it can't be associated with something that is already known to be bad.

        Certainly you have all read articles that 'supplements are a waste, don't take them, they don't do anything'. That conflicts with everything we're talking about. It can be said many are of questionable value, many are indeed worthless, and many have a specific use that unfortunately can't be legally stated and either never get the recognition they deserve, or get branded as bad.

        Would we have people bleeding out of their eyes from buying adultered synthetic marijuana? That would not be an issue if they could get the real thing legally. No one would be adding the rat poison to their rolling papers because of a profit motive. The people that adulterated the synthetic marijuana batch did it to use less of the actual drug since the blood thinner involved helps increase the potency of the synthetic thc. I won't even get started on how there is research that shows marjiuana helps wean people off various addictions. We have naloxone and continued long-term treatment programs for that, I guess.

        The four things I mentioned are in the same "supplements" category, yet the FDA has gone out of their way to eliminate or prevent due to clear competition with a more expensive "proper" product. I expect the "don't take supplements" is just propganda based on some truths, but more based on profits. Don't take red yeast rice powder because it actually works and there is this licensed other product that needs your money, etc...

        (And despite what I am saying, I am not saying everything should be packaged neatly and sold to anyone that wants it. I can't quite support anyone taking too much jimson weed laced with hemlock--so yeah, not all natural products are good when taken inappropriately.)

         

    • (Score: 3, Insightful) by frojack on Saturday April 07 2018, @03:22AM (2 children)

      by frojack (1554) on Saturday April 07 2018, @03:22AM (#663639) Journal

      Again, with the right kind of support the addicts would carry Naloxone,

      They don't want your damn support. When will you get this through your head!!?

      They routinely and repeatedly refuse treatment, they know they are heading toward the grave, and all they want is to make sure they have enough drugs for the final journey.

      Only 20% of heroin addicts seek treatment, (usually at the insistence of others or the legal system) and of those the relapse rate is usually over 91 percent.
      https://drugabuse.com/library/heroin-relapse/ [drugabuse.com]

      You are delusional if you believe they want your "support".

      --
      No, you are mistaken. I've always had this sig.
      • (Score: 3, Interesting) by JoeMerchant on Saturday April 07 2018, @03:34AM (1 child)

        by JoeMerchant (3937) on Saturday April 07 2018, @03:34AM (#663648)

        I know that most of them die, and most of them are not well integrated with society while they are on their way out.

        In the circles I travel, I don't interact with the ones on their way down - I do know several who have made it back from the pit and 10+ years later are still clean.

        You are delusional if you believe they want your "support".

        For the ones who want to check out, I actually support that - give them the option for help, and the help to not conflict with the rest of the world on their way out if they choose to keep using. I was just passing through, but in the 1990s the Zurich train station park [swissinfo.ch] seemed like a place where that was happening, and I think there are many similar things that still go on in Europe. It seems like a much better approach than Miami where you have transvestite prostitutes with an average life expectancy of less than a year working Biscayne Boulevard in the evenings, and breaking into whatever they can during the day for money to score with.

        --
        🌻🌻 [google.com]
        • (Score: -1, Redundant) by Anonymous Coward on Saturday April 07 2018, @07:48PM

          by Anonymous Coward on Saturday April 07 2018, @07:48PM (#663785)

          I want to know who pays for the treatment of people that couldn't afford treatment? Do we need another tax cut to get that funded?