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Americans die of heart or cardiovascular disease at an alarming rate. In fact, heart attacks, strokes and related diseases will kill an estimated 610,000 Americans this year alone. Some medications help, but to better tackle this problem, researchers need to know exactly how the heart and blood vessels stay healthy in the first place.
Now, scientists at The Scripps Research Institute have identified a protein, called GPR68, that senses blood flow and tells small blood vessels called arterioles when to dilate. The researchers believe medications that activate GPR68 could one day be useful to treat medical conditions, including ischemic stroke.
"It has been known for decades that blood vessels sense changes in blood flow rate, and this information is crucial in regulating blood vessel dilation and controlling vascular tone," says Ardem Patapoutian, PhD, Scripps Research professor, Howard Hughes Medical Institute investigator and senior author of the study published today in the journal Cell.
(Score: 2) by crafoo on Saturday April 21 2018, @09:41AM (3 children)
Pretty interesting story. The machine they used to simulate blood flow in a organism is fascinating and not something I expected.
Also though, a reminder to not eat everything within arms reach (unless it's green, leafy plants). As a preventive measure to heart disease. Sugars and starches kill.
(Score: 3, Interesting) by JoeMerchant on Saturday April 21 2018, @11:51AM (2 children)
This [businesswire.com] company [reuters.com] (and this one [vasomedical.com] too) made/makes a device, starting about 20 years ago, to mechanically induce FMD in people who can not exercise on their own. Was surprisingly effective at increasing circulation in all sorts of disease states in which reduced bloodflow exacerbated the condition. Not terribly commercially successful for either, market caps running 6-7M these days; indicates a company that is running out of some low rent space somewhere with 10 FTE and 1M annual revenue, not a bad place to start, but is an unexciting place to end up after 20 years of operations.
🌻🌻 [google.com]
(Score: 2) by JoeMerchant on Saturday April 21 2018, @11:54AM (1 child)
I keep forgetting that less-than symbols are invisified by the soylent editor!
🌻🌻 [google.com]
(Score: 2) by RS3 on Saturday April 21 2018, @06:21PM
You can use < and >
...
but, every time you "Preview" (and we all do that before "Submit", right? usually...), the preview processor will strip your < and replace it with <, which won't render as a literal less-than sign, so you have to edit the comment one last time before hitting "Submit". Hope that helps.