SoylentNews is people
SoylentNews
Scientists at Osaka University discovered that Stromal derived factor-1 (SDF-1) secreted from adipocytes reduced the effectiveness of insulin in adipocytes and decreased insulin-induced glucose uptake.
[...] Using microarray database analysis, this group of scientists identified SDF-1 as a factor to enhance expression in adipocytes in both fasting and obese states and found that SDF-1 reduced the effectiveness of insulin in adipocytes. In actuality, in SDF-1 knockout mice, insulin-induced glucose uptake increased (i.e., blood sugar levels decreased), and insulin efficacy improved (i.e., insulin sensitivity was enhanced). Their research results were published in Diabetes.
Based on the results of this study, it is expected that insulin sensitivity in adipocytes will increase by inactivating the SDF-1 signaling pathway, which will lead to treatment of obese type 2 diabetes.
(Score: 3, Insightful) by Booga1 on Friday April 27 2018, @02:16AM (2 children)
If this holds true, this could be a serious breakthrough. I've lost multiple friends to diabetes and nearly lost family as well. I hope this can become a treatment post-haste!
(Score: 5, Interesting) by Phoenix666 on Friday April 27 2018, @11:33AM
Agreed. It would be a bonus if this sheds light on stubborn obesity, too.
Washington DC delenda est.
(Score: 0) by Anonymous Coward on Friday April 27 2018, @08:14PM
You do realize that this condition already has ample ways of avoiding it, right? If you don't get fat and you don't overcomsume sugar, you're not going to get this type of diabetes. If you've got it, losing weight, cutting out the sugary garbage, exercising and fasting can set things back the way that they were supposed to be.
The disorder that really needs a real treatment is insulin dependent diabetes. There's not much that can be done about it at present as the body isn't producing enough insulin and it's not something that's generally avoidable.