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[...] The research team studied the medical records of 40,770 patients aged over 65 diagnosed with dementia, and compared them to the records of 283,933 people without dementia. More than 27 million prescriptions were analysed.
[...] They found that there was a greater incidence of dementia among patients prescribed greater quantities of anticholinergic antidepressants, and anticholinergic medication for bladder conditions and Parkinson's.
[...] "We studied patients with a new dementia diagnosis and looked at what anticholinergic medication they were prescribed between four and 20 years prior to being diagnosed.
"We found that people who had been diagnosed with dementia were up to 30 per cent more likely to have been prescribed specific classes of anticholinergic medications. And the association with dementia increases with greater exposure to these types of medication.
"What we don't know for sure is whether the medication is the cause. It could be that these medications are being prescribed for very early symptoms indicating the onset of dementia.
"But because our research shows that the link goes back up to 15 or 20 years before someone is eventually diagnosed with dementia, it suggests that reverse causation, or confounding with early dementia symptoms, probably isn't the case.
(Score: -1, Spam) by Anonymous Coward on Sunday April 29 2018, @03:14AM
A pitch black room. A sound. A continuous sound. If, by some miracle, one could manage to see in this room, they would spot a grown man sobbing in the corner. It was clear that this man, Brendonham, had succumbed to despair. What awful event transpired to turn a grown man into a sobbing child? Broken. Everything broke.
Just earlier that day, Brendonham was happier than could be. You see, he had acquired a large number of toys, and he intended to play with them for the next few weeks. However, something went wrong. Something went terribly wrong. One after another, one by one, the toys broke in quick succession. These toys were supposed to last for weeks, and yet Brendonham had managed to break them all in a mere hour! Indeed, the man had gotten a bit too playful, and now all that was left was garbage.
Yes, garbage. The corpses of the children which surrounded Brendonham were nothing but garbage to him; they could not scream; they could not squeal; they could not have seizures; they could not beg for mercy. Due to this, violating them was no fun at all for Brendonham! And so, the man sobbed. The man sobbed because his toys were broken. The man sobbed because he would need to acquire new ones, which meant more work for him. The man sobbed because he knew the new toys wouldn't last any longer. The man sobbed.
Anyone who looked at Brendonham would feel sorry for him, and would promptly be reduced to tears. Poor Brendonham! Poor, poor Brendonham. However, the hideous, obese man slowly rose from his spot in the corner. An unfortunate event such as this would not be enough to completely break this man's iron will. Brendonham would acquire new toys. Brendonham would play these toys. And Brendonham would have fun!
Brendonham looked forward, his eyes brimming with determination. The brave man took one step, and then another. Onward! This man was extraordinary. And many good things lie in wait for extraordinary individuals. Toys, and happiness.