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posted by Fnord666 on Friday May 18 2018, @06:45PM   Printer-friendly
from the research-that-just-scratches-the-surface dept.

Submitted via IRC for Bytram

For some people, particularly those who are elderly, even a light touch of the skin or contact with clothing can lead to unbearable itching. What's worse, anti-itch treatments, including hydrocortisone, don't provide much relief for this type of itching.

Now, researchers at Washington University School of Medicine in St Louis have discovered, in mice, why a touch can cause such severe itching and, in the process, identified some possible therapeutic targets.

Their research, published May 4 in the journal Science, indicates that itching caused by touch is directly related to the number of touch receptors embedded in the skin. The fewer the receptors, the more likely it is that touching will induce itching.

Source: https://medicine.wustl.edu/news/when-light-touches-of-the-skin-cause-itching/

Jing Feng, Jialie Luo, Pu Yang, Junhui Du, Brian S. Kim, Hongzhen Hu. Piezo2 channel–Merkel cell signaling modulates the conversion of touch to itch. Science, 2018; 360 (6388): 530 DOI: 10.1126/science.aar5703


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  • (Score: 3, Interesting) by MichaelDavidCrawford on Friday May 18 2018, @07:35PM (3 children)

    Because depakote caused severe chronic itching. I changed to Trileptal for both mania and seizures. The itching wasn't as severe but persisted for a few years

    Bonita said I looked like I had lice

    Steroid creams don't help not even a little bit

    The itching is finally starting to subside. I don't bleed much anymore

    --
    Yes I Have No Bananas. [gofundme.com]
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  • (Score: -1, Troll) by Anonymous Coward on Friday May 18 2018, @07:48PM (1 child)

    by Anonymous Coward on Friday May 18 2018, @07:48PM (#681346)

    What a beautiful day. The man, Winkelham, who was merely an observer, truly thought this to be so. Yes, Winkelham was but an observer; since he was a mere perspective, he could not affect anything with his actions. And so, he continued to observe his surroundings. Then, Winkelham spotted a small girl, and moved closer so that he could observe her in more detail.

    Intense. Winkelham's gaze was truly intense. The man observed the little girl with every fiber of his being, and then observed her some more. More. More. More! Winkelham couldn't get enough of it, so he used True Observation to observe every aspect of her being. That did it.

    Winkelham, who had finished observing the little girl, returned to his former spot in the park to continue watching his surroundings. The man's gaze did not once return to the naked, violated corpse of the little girl, who was no longer even worthy of it...

  • (Score: 1, Informative) by Anonymous Coward on Saturday May 19 2018, @05:25AM

    by Anonymous Coward on Saturday May 19 2018, @05:25AM (#681521)

    Have you tried unfiltered hemp seed oil? On the skin to relieve itching.