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F.D.A. Approves First Drug Designed to Prevent Migraines
The first medicine designed to prevent migraines was approved by the Food and Drug Administration on Thursday, ushering in what many experts believe will be a new era in treatment for people who suffer the most severe form of these headaches. The drug, Aimovig, made by Amgen and Novartis, is a monthly injection with a device similar to an insulin pen. The list price will be $6,900 a year, and Amgen said the drug will be available to patients within a week.
Aimovig blocks a protein fragment, CGRP, that instigates and perpetuates migraines. Three other companies — Lilly, Teva and Alder — have similar medicines in the final stages of study or awaiting F.D.A. approval. "The drugs will have a huge impact," said Dr. Amaal Starling, a neurologist and migraine specialist at the Mayo Clinic in Phoenix. "This is really an amazing time for my patient population and for general neurologists treating patients with migraine."
Millions of people experience severe migraines so often that they are disabled and in despair. These drugs do not prevent all migraine attacks, but can make them less severe and can reduce their frequency by 50 percent or more. As a recent editorial in the journal JAMA [DOI: 10.1001/jama.2018.4852] [DX] put it, they are "progress, but not a panacea."
Sticker shock? The price is 30% less than Wall Street expected. Meanwhile, people are self-administering psychedelics such as LSD or psilocybin to treat migraines and cluster headaches.
(Score: 0) by Anonymous Coward on Monday May 21 2018, @09:58PM (7 children)
Am I an incel even if I have a sex doll?
(Score: 0) by Anonymous Coward on Monday May 21 2018, @10:04PM (2 children)
Has the term "volcel" come into vogue yet, to distinguish between voluntary and involuntary celibates?
(Score: 2) by takyon on Monday May 21 2018, @10:52PM
Apparently, "volcel" [reddit.com] does exist, but I think it's probably better known under the umbrella of (men|man) going (their|his) own way [wikia.com], aka MGTOW or MGHOW. Although volcel and incel can encompass people of any gender.
The term "incel" is likely to inspire more ridicule, hate, self-loathing, etc., because of the obvious contradiction in what an incel wants and what they get, which could theoretically lead to frustration and violence. With two recent mass murder incidents being pinned on "incels", we could be hearing that term a lot more.
There's also "asexual", which is an orientation that may include having sex (that you aren't really into) according to this source [asexualityarchive.com].
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(Score: 0) by Anonymous Coward on Monday May 21 2018, @11:12PM
> Has the term "volcel" come into vogue yet
Doesn't the Catholic church have dibs on that concept (by other names)?
Not that every priest who takes the vow actually lives up to the vow...
(Score: 0) by Anonymous Coward on Monday May 21 2018, @10:34PM (3 children)
Hmm... yes. Most definitely. In fact, even if you also have a flesh-and-blood lady friend, I'm certain the sex doll makes you an incel.
Though mostly I think the word incel is just the CIA setting the stage for a return to military conscription, which is why I picked somebody opposing transnational immortal corporation copyrights and here I pick out somebody opposing big pharma's collusion with the DEA to commoditize and profit off things that Mother Nature provides to us free of charge.
First there was #gamergate (and I should have noticed that there was something distinctly un-feminist about it... but came to the opposite conclusion instead). Then the misogynerd narrative. There was some whargarbl about homosexual men and furries being failed men, but not as a major narrative in the mainstream press. Now incels. The common pattern is the creation of classes of "failed men." This speaks more to male chauvinism than anything feminist.
Think also about She Lost. Hillary Clinton was the choice of the CIA. Then She Lost. Now there's #metoo, which targets all kinds of people who might speak up and use their position as artists/filmmakers/etc to oppose World War 3. Actually, of all those things, #metoo is the only thing remotely feminist, but that could be stopped watch effect.
Wait about another year or two or three or so, and I guarantee that conscription will be seriously discussed. The MIC will just handily have the solution to all these failed men. Send them to die in World War 3, and that will turn them into real men. Plenty of villages we need to burn in order to save.
Note also the real reason these "failed men" exist: it's the economy, stupid. Of course the CIA doesn't want anybody talking about that. We can focus on failed men instead. Blame the victim. There's just something wrong with them. Them--they're Others. So it's natural the CIA will be selling the solution. Service guarantees citizenship!
(Score: 2) by takyon on Monday May 21 2018, @11:10PM (2 children)
Conscription will not be seriously discussed without an equally serious discussion of conscripting women. Although you could imagine that women could be forced or coaxed into less demanding combat roles.
Will WW3 require conscription? Automation might make it unnecessary. I was going to write something about conscripting women into factories, but factory work is increasingly moving back to the U.S. because fewer workers are needed to run one (except the Musky One can't grok it [techcrunch.com]). On the war front we have drones being the most attractive weapon by far. You could see robots or mechs replacing "boots on the ground", but not within the next 1-3 years.
But the real question here is: what do you mean by WW3? If it's a nuclear conflict, you don't need to conscript anybody, and you don't have time to do so, because it would be decided in minutes or hours. What will cause a global nuclear conflict? North Korea? U.S. probably has some informal agreement with China where we get to burn NK to a crisp if they do a first strike on the South. India vs. Pakistan? Doubtful.
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(Score: 2) by Azuma Hazuki on Tuesday May 22 2018, @04:33AM (1 child)
What she means is trolololololol, that's what. That's probably Kurenai or one of her alts.
I am "that girl" your mother warned you about...
(Score: 2) by takyon on Tuesday May 22 2018, @05:06AM
I choose to respond to the content of the comment. Or at least a part of it.
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