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posted by takyon on Tuesday June 05 2018, @02:45AM   Printer-friendly

Submitted via IRC for SoyCow8093

An evolutionary adaptation that doesn't directly rely on new mutations - Blind cave fish harnessed an epigenetic system to shut down eye development

Mexican tetra swam from surface waters into their caves around 1.5 million years ago. Like naked mole rats—another species that lives underground, in perennial darkness—they have no eyes. But whereas key genes controlling eye development in naked mole rats have mutations that inactivate them, there are no such inactivating mutations in the genes of the Mexican cave fish.

But mutations aren't the only way to change gene activity, and new research suggests a different explanation for the fish's lack of eyes. Epigenetic regulation is a means of controlling gene activity that does not alter the DNA sequence of the genes themselves. Genes undergoing epigenetic regulation can still make normal proteins, but the amount of the protein they make is modulated.

One method of epigenetic regulation is the addition of methyl groups to the DNA that controls the activity of specific genes. It is efficient, since it can be used to alter a whole bunch of genes at once. And it seems to explain the Mexican cave fish eye degeneration that has occurred over the past million years—a proverbial blink of an eye in evolutionary terms.

An epigenetic mechanism for cavefish eye degeneration (DOI: 10.1038/s41559-018-0569-4) (DX)


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  • (Score: -1, Troll) by Anonymous Coward on Tuesday June 05 2018, @03:00AM (1 child)

    by Anonymous Coward on Tuesday June 05 2018, @03:00AM (#688699)

    It's no different "a lifeform uses biology to defecate".

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  • (Score: 3, Informative) by takyon on Tuesday June 05 2018, @03:18AM

    by takyon (881) <takyonNO@SPAMsoylentnews.org> on Tuesday June 05 2018, @03:18AM (#688704) Journal

    "... into an AC's gaping maw."

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