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posted by CoolHand on Tuesday July 03 2018, @02:21PM   Printer-friendly

Arthur T Knackerbracket has found the following story:

A new therapeutic may help reverse chemical imbalances made to the brain by habitual drug use and could one day help recovering drug addicts avoid future drug use.

Researchers from The University of Texas Medical Branch at Galveston developed and tested a treatment on rats and found it effective in reducing the animals' cravings. Their findings are in the Journal of Medicinal Chemistry.

When someone habitually misuses drugs, their brain chemistry is changed in ways that make it harder for them to quit taking drugs despite negative consequences. Once someone has developed this brain disorder, their mind pays sharper attention to cues that encourage drug use, making it harder for them to abstain.

Serotonin, a brain chemical that transmits information between neural regions, is a key player in these changes. There are currently no medications available to correct this chemical imbalance.

UTMB pharmacology and toxicology professors Jia Zhou, Kathryn Cunningham and their colleagues found that the serotonin 2C receptors in drug addicts do not work as well as they should. They designed, synthesized and pharmacologically evaluated a series of small molecule therapeutics designed to restore the weakened signaling.

-- submitted from IRC


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  • (Score: 3, Informative) by mhajicek on Tuesday July 03 2018, @07:07PM

    by mhajicek (51) on Tuesday July 03 2018, @07:07PM (#702105)

    Economic inequality is a big factor. Those in power only want to increase it though. "It is not enough that I succeed, others must fail."

    --
    The spacelike surfaces of time foliations can have a cusp at the surface of discontinuity. - P. Hajicek
    Starting Score:    1  point
    Moderation   +1  
       Informative=1, Total=1
    Extra 'Informative' Modifier   0  
    Karma-Bonus Modifier   +1  

    Total Score:   3