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Male mice grow ovaries instead of testes if they are missing a small region of DNA that doesn't contain any genes, finds a new paper published in Science.
The study, led by researchers at the Francis Crick Institute, could help explain disorders of sex development in humans, at least half of which have an unknown genetic cause.
Mammals will develop ovaries and become females unless the early sex organs have enough of a protein called SOX9 at a key stage in their development. SOX9 causes these organs to become testes, which then direct the rest of the embryo to become male.
Sex reversal following deletion of a single distal enhancer of Sox9 (DOI: 10.1126/science.aas9408) (DX)
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Non-Coding DNA Changes the Genitals You're Born With
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(Score: 0) by Anonymous Coward on Wednesday July 04 2018, @08:47AM (2 children)
I presume this can be used reduce the male population and the general aggression of the human race.
Maybe humanity can bottle up the Y chromosome completely, assuming the XY ovaries no longer produce mobile sperm.
This needs a Hollywood adaptation, or at least a Best Seller fiction novel. :)
(Score: 2) by Bot on Wednesday July 04 2018, @12:53PM (1 child)
> reduce the male population and the general aggression of the human race
It will surely be peaceful when many females will compete for the attention of few males.
Account abandoned.
(Score: 0) by Anonymous Coward on Wednesday July 04 2018, @02:51PM
Ummm... I've been in that position, still am. If #MeToo applied to guys, and all the way back to the late 1970s, holy shit. Some stories belong in "Dear Penthouse".