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posted by mrpg on Wednesday July 04 2018, @03:58AM   Printer-friendly
from the don't-touch-my-genitals dept.

Submitted via IRC for takyon

Male mice grow ovaries instead of testes if they are missing a small region of DNA that doesn't contain any genes, finds a new paper published in Science.

The study, led by researchers at the Francis Crick Institute, could help explain disorders of sex development in humans, at least half of which have an unknown genetic cause.

Mammals will develop ovaries and become females unless the early sex organs have enough of a protein called SOX9 at a key stage in their development. SOX9 causes these organs to become testes, which then direct the rest of the embryo to become male.

Source: https://www.crick.ac.uk/news/science-news/2018/06/14/non-coding-dna-changes-the-genitals-youre-born-with/

Sex reversal following deletion of a single distal enhancer of Sox9 (DOI: 10.1126/science.aas9408) (DX)


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  • (Score: 0) by Anonymous Coward on Wednesday July 04 2018, @05:17PM (1 child)

    by Anonymous Coward on Wednesday July 04 2018, @05:17PM (#702631)

    DNA has a quaternary encoding, not a binary one.

  • (Score: 2) by Bot on Wednesday July 04 2018, @09:39PM

    by Bot (3902) on Wednesday July 04 2018, @09:39PM (#702744) Journal

    GP was not saying DNA encoding is binary though.

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