Stories
Slash Boxes
Comments

SoylentNews is people

posted by martyb on Sunday August 05 2018, @02:46AM   Printer-friendly
from the life-will-find-a-way dept.

Bacteria are becoming resistant to alcohol-based disinfectants:

Because of the growing numbers of so-called superbugs, hospitals have introduced more stringent cleaning routines. Part of the regimen involves alcohol-based disinfectants, such as hand rubs, positioned in and around hospital wards. Since their introduction, there has been a significant reduction in the number of hospital-based infections. Containing 70 percent isopropyl or ethyl alcohol, alcohol-based hand rubs kill bacteria quickly and effectively.

Over recent years, researchers have noted a steady rise in the number of serious infections caused by one particular drug-resistant bacterium — Enterococcus faecium. Despite the wide use of alcohol-based disinfectants, E. faecium is now a leading cause of hospital-acquired infections. Dr. Sacha Pidot and his colleagues at the University of Melbourne in Australia set out to understand whether this increased infection rate might be because the bacterium is growing resistant to alcohol. Their findings were published this week in the journal Science Translational Medicine [DOI: 10.1126/scitranslmed.aar6115] [DX].

Also at Live Science.

Increasing tolerance of hospital Enterococcus faecium to handwash alcohols:

Alcohol-based disinfectants and particularly hand rubs are a key way to control hospital infections worldwide. Such disinfectants restrict transmission of pathogens, such as multidrug-resistant Staphylococcus aureus and Enterococcus faecium. Despite this success, health care infections caused by E. faecium are increasing. We tested alcohol tolerance of 139 hospital isolates of E. faecium obtained between 1997 and 2015 and found that E. faecium isolates after 2010 were 10-fold more tolerant to killing by alcohol than were older isolates. Using a mouse gut colonization model of E. faecium transmission, we showed that alcohol-tolerant E. faecium resisted standard 70% isopropanol surface disinfection, resulting in greater mouse gut colonization compared to alcohol-sensitive E. faecium. We next looked for bacterial genomic signatures of adaptation. Alcohol-tolerant E. faecium accumulated mutations in genes involved in carbohydrate uptake and metabolism. Mutagenesis confirmed the roles of these genes in the tolerance of E. faecium to isopropanol. These findings suggest that bacterial adaptation is complicating infection control recommendations, necessitating additional procedures to prevent E. faecium from spreading in hospital settings.


Original Submission

 
This discussion has been archived. No new comments can be posted.
Display Options Threshold/Breakthrough Mark All as Read Mark All as Unread
The Fine Print: The following comments are owned by whoever posted them. We are not responsible for them in any way.
  • (Score: 5, Interesting) by MostCynical on Sunday August 05 2018, @03:53AM (5 children)

    by MostCynical (2589) on Sunday August 05 2018, @03:53AM (#717427) Journal

    The problem is that people *didn't* overuse plain old soap, as washing hands properly takes too long.
    Alcohol is faster and easier.

    --
    "I guess once you start doubting, there's no end to it." -Batou, Ghost in the Shell: Stand Alone Complex
    Starting Score:    1  point
    Moderation   +3  
       Insightful=1, Interesting=2, Total=3
    Extra 'Interesting' Modifier   0  
    Karma-Bonus Modifier   +1  

    Total Score:   5  
  • (Score: 0, Disagree) by Anonymous Coward on Sunday August 05 2018, @05:14AM (2 children)

    by Anonymous Coward on Sunday August 05 2018, @05:14AM (#717439)

    The people who don't wash their hands don't get sick. It's you people who spend three hours each day washing your hands who get sick. Now, stop whining and let me eat my germ-laden lunch in peace.

    • (Score: 4, Touché) by tfried on Sunday August 05 2018, @06:24AM (1 child)

      by tfried (5534) on Sunday August 05 2018, @06:24AM (#717444)

      It seems you may be missing the key point about hand washing/disinfection in hospitals. No, it's not about the staff and visitors not getting sick.

      Excessive hygiene at home is a different story altogether.

      • (Score: 2) by PartTimeZombie on Sunday August 05 2018, @10:47PM

        by PartTimeZombie (4827) on Sunday August 05 2018, @10:47PM (#717650)

        My local supermarket supplies alcohol handwipes so people can clean the handle on their cart.

        I prefer exposure to lots of different micro-organisms, so that I can develop my own immunity to them. (Obviously not including the really naughty ones. I'm not some sort of anti-vaxxer).

  • (Score: 2) by realDonaldTrump on Sunday August 05 2018, @09:37PM (1 child)

    by realDonaldTrump (6614) on Sunday August 05 2018, @09:37PM (#717627) Homepage Journal

    I would be a tremendous doctor. Because I happen to be a clean hands freak. I feel much better after I thoroughly wash my hands, which I do as much as possible. I'm a very clean person. I like cleanliness. One of the curses of American society is the simple act of shaking hands, and the more successful and famous one becomes the worse this terrible custom seems to get. I find myself thinking more and more about Howard Hughes, and even, to some degree, identifying with him. To many people today he symbolizes weirdness. He is probably doomed to be remembered as the guy with the long fingernails and the wild hair. That’s a shame, because here was a guy who at one time was movie-star handsome, a certified billionaire, and a genius in several fields. Hughes had it all, and judging by the number of beautiful ex-girlfriends who are still writing books about him, he seemed, for a while at least, to be living life TO THE HILT. Yet the pressure of being a larger-than-life figure was apparently so mind-boggling that it gradually drove him crazy. Too bad!!!