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It is well established that stress can alter the activation pattern of our genes. Stress also triggers epigenetic mechanisms which modulate how DNA, the carrier of genetic information, is read. The genetic information on the DNA is in the next step ‘translated’ into RNA, which is the blueprint of proteins. In a groundbreaking study, scientists at the Max Planck Institute of Psychiatry (MPI) have shown for the first time that stress can also cause similar “epigenetic” changes on the RNA level. The research results were recently published in the internationally renowned journal Neuron.
It was recently rediscovered that RNA can be modified by chemical tags in a similar way to the epigenetic modifications seen on DNA. Messenger RNA (mRNA) is made up of four molecular building blocks: adenosine, cytidine, guanosine and uridine, which can be modified by the attachment of chemical tag. These tags or RNA modifications provide a sophisticated extra layer of gene regulation.
A modification of mRNA, which occurs post-transcriptionally is methylation of adenosine and the most abundant is N6-methyladenosine (m6A). Although m6A was first described in 1974, recent technological advances were necessary before more detailed analyses of the epitranscriptome could be carried out.
[...] Alon Chen, Director at the Institute and head of the project explains: “Increasing evidence suggests that the fine-tuning seen with mRNA methylation may underlie the etiology of psychiatric disorders. We think that elucidating the role of mRNA methylation in regulating brain function will help us to better understand psychiatric disorders.”
(Score: 0) by Anonymous Coward on Tuesday August 14 2018, @01:19PM (2 children)
Americans, Jews, Muslims, and the warmongering tribes of Africa subject boys to an extremely painful ordeal.
I wonder what effect this has had on their populations.
Besides the physical trauma, Muslim boys are particularly subjected to the psychological trauma, as it is traditional to do this to them around the age 7-to-12 years old, often en masse (certainly common in Malaysia and Turkey). Similarly, upwards of one hundred young tribal teenagers die in South Africa every year or so when forcibly circumcised.
What does cutting up the sexual organs of half the population do, especially it is forced upon them at tender ages? How does it affect gender relations, and how does it train both the bodies and minds of young men in their approach to dealing with the world at large?
(Score: 0) by Anonymous Coward on Tuesday August 14 2018, @01:43PM
Circumcision trains a boy to rape a virgin in a vain attempt to regain his lost foreskin by breaking her hymen.
(Score: 2) by Azuma Hazuki on Tuesday August 14 2018, @11:09PM
It's got to mess them up badly, even if done to them as little babies. This is one reason my particular brand of feminism has a very strong anti-circumcision streak to it: if nothing else, one way to knock down the rate of men abusing women is to stop people in general abusing boys in the first place, and yes, this IS a form of childhood physical and sexual abuse. Leave our babies alone, ALL of them.
I am "that girl" your mother warned you about...