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3-in-1 Vaccine Against Traveler's Diarrhea

posted by chromas on Saturday October 13 2018, @02:56AM   Printer-friendly
from the di–arrhea!-d–i–arrhea! dept.

"upstart" writes:

Submitted via IRC for Bytram

3-in-1 vaccine against traveler's diarrhea

A first-ever vaccine designed to deliver a one-two-three punch against the main causes of traveller's diarrhea worldwide may result from new research published by a University of Guelph chemist.

Prof. Mario Monteiro says his novel three-in-one approach to developing a new vaccine could also save lives in developing countries, where it's estimated that these three common pathogens kill more than 100,000 children under age five each year.

His research was recently published in the journal Vaccine.

The paper discusses Monteiro's so-called conjugate vaccine that yokes together proteins from pathogenic E. coli with sugars from Shigella and Campylobacter jejuni. All three bugs are major causes of bacterial diarrhea globally.

In tests with mice, the vaccine provided immunity against all three pathogens.

Evaluation of a conjugate vaccine platform against enterotoxigenic Escherichia coli (ETEC), Campylobacter jejuni and Shigella. Vaccine, 2018; DOI: 10.1016/j.vaccine.2018.09.052

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  • (Score: 1, Interesting) by Anonymous Coward on Saturday October 13 2018, @04:24AM (1 child)

    by Anonymous Coward on Saturday October 13 2018, @04:24AM (#748170)

    Diarrhea builds character.

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  • (Score: 2, Funny) by Anonymous Coward on Saturday October 13 2018, @11:12AM

    by Anonymous Coward on Saturday October 13 2018, @11:12AM (#748266)

    I built some character last week: stomach troubles had left my bum a bit sensitive. The last day of the trip included a dip in the Dead Sea. You are warned not to shave before entering the super salty solution, but this caught me completely off guard!