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3-in-1 vaccine against traveler's diarrhea
A first-ever vaccine designed to deliver a one-two-three punch against the main causes of traveller's diarrhea worldwide may result from new research published by a University of Guelph chemist.
Prof. Mario Monteiro says his novel three-in-one approach to developing a new vaccine could also save lives in developing countries, where it's estimated that these three common pathogens kill more than 100,000 children under age five each year.
His research was recently published in the journal Vaccine.
The paper discusses Monteiro's so-called conjugate vaccine that yokes together proteins from pathogenic E. coli with sugars from Shigella and Campylobacter jejuni. All three bugs are major causes of bacterial diarrhea globally.
In tests with mice, the vaccine provided immunity against all three pathogens.
Evaluation of a conjugate vaccine platform against enterotoxigenic Escherichia coli (ETEC), Campylobacter jejuni and Shigella. Vaccine, 2018; DOI: 10.1016/j.vaccine.2018.09.052
(Score: 2) by Azuma Hazuki on Saturday October 13 2018, @05:40AM (3 children)
This sounds encouraging, since there's little risk of actually giving someone an infection with said organisms; rather, it looks to prime the immune system against their secretions. IIRC this is how the tetanus shot works, and that's one of the more effective ones I know of. Good to see this happening, especially because of how many peopel diarrhea kills and how horribly, something very few Americans truly understand...
I am "that girl" your mother warned you about...
(Score: 2) by Kilo110 on Saturday October 13 2018, @07:33AM (1 child)
"something very few Americans truly understand..."
sadly it's become better known in certain communities
https://arstechnica.com/science/2018/01/fear-tap-water-is-a-toxic-plot-to-control-your-mind-heres-the-water-for-you/ [arstechnica.com]
(Score: 0) by Anonymous Coward on Saturday October 13 2018, @09:06AM
https://www.youtube.com/watch?v=Qr2bSL5VQgM [youtube.com]
(Score: 0) by Anonymous Coward on Saturday October 13 2018, @09:02AM
Infant mortality is the #1 reason for high birth rates.