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posted by martyb on Saturday March 02 2019, @07:11PM   Printer-friendly
from the debugging dept.

The spread of antimicrobial resistance in hospitals can be limited by sanitation methods that remodulate the hospital microbiota, leading to lower antimicrobial consumption and costs, according to a paper in Infection and Drug Resistance co-authored by two Bocconi University scholars (for the part related to costs) with University of Ferrara and colleagues from University of Udine.

In particular, an experiment conducted in five Italian hospitals using the Probiotic Cleaning Hygiene System (PCHS), a trademarked probiotic-based sanitation method, coordinated by the CIAS research centre of the University of Ferrara (www.cias-ferrara.it) , led to a 52% decrease in healthcare associated infections (HAI, a kind of infection that tend to exhibit higher resistance to antibiotics than community-acquired infections), a 60.3% reduction in associated drug consumption and a 75.4% decrease in the related costs. «The results», Bocconi University's Rosanna Tarricone, co-author of the study, says, «suggest that the introduction of probiotic-based sanitation methods can be considered as a useful component of infection prevention strategies. Money saving are only a part of the story, as HAIs affect 3.2 million people in Europe every year, resulting in 37,000 deaths».

The Internal Medicine wards of the hospitals enrolled in the study were surveyed for six months while using the conventional chemical-based sanitation method and, then, for a further six months using ecologically sustainable detergents containing spores of three Bacillus species. Overall 12,000 patients were included in the study and over 30,000 environmental samples from hospital surfaces were analyzed.

The new sanitation system was associated with a mean 83% decrease of the detected pathogens on hospital surfaces and a significant reduction (70-99.9%) of antimicrobial resistant genes. In the case of Staphylococcus aureus (Staphylococcus spp. represented up to 90% of the total surface microbiota detected and S. aureus, in particular, plays an important role in HAIs), the isolates from the post-intervention phase were 63.9-93.5% less resistant to antibiotics, depending on the antibiotic type, and those resistant to three or more antibiotics decreased by 72.4%.

The number of healthcare associated infections diminished by 52%, as detailed in another co-authored paper (PLoS ONE 13(7): e0199616), and the cost per HAI episode diminished by 45.6%, translating into the aforementioned 60.3% reduction in associated drug consumption and 75.4% decrease in related costs.

Since the analysis focused only on drug costs, «taking into account other variables, such as the length of stay in hospital, our estimates of the savings are likely to be conservative», concludes Carla Rognoni, the other Bocconi University co-author of the paper.

Journal Reference:
Elisabetta Caselli, et. al. Impact of a probiotic-based hospital sanitation on antimicrobial resistance and HAI-associated antimicrobial consumption and costs: a multicenter study Infection and Drug Resistance, 2019; Volume 12: 501 DOI: 10.2147/IDR.S194670


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  • (Score: 1, Insightful) by Anonymous Coward on Saturday March 02 2019, @08:42PM (10 children)

    by Anonymous Coward on Saturday March 02 2019, @08:42PM (#809238)

    For some reason, all the group 11 elements are anti-bacterial: https://en.wikipedia.org/wiki/Periodic_table#/media/File:Simple_Periodic_Table_Chart-en.svg [wikipedia.org]

    All they need to do is make every surface out of copper, silver, gold, or roentgenium. Most likely copper would be chosen since that is the cheapest of the three.

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  • (Score: 2, Informative) by pTamok on Saturday March 02 2019, @09:03PM (3 children)

    by pTamok (3042) on Saturday March 02 2019, @09:03PM (#809243)

    Oddly enough people do.

    Wikipedia:Antimicrobial copper-alloy touch surfaces [wikipedia.org]

    • (Score: 3, Funny) by c0lo on Sunday March 03 2019, @12:33AM (2 children)

      by c0lo (156) Subscriber Badge on Sunday March 03 2019, @12:33AM (#809288) Journal

      If you are of the oddly people, there's a chance to use copper-alloy touch surfaces.
      I wonder what the evenly enough people do?

      --
      https://www.youtube.com/watch?v=aoFiw2jMy-0 https://soylentnews.org/~MichaelDavidCrawford
      • (Score: 3, Informative) by pTamok on Sunday March 03 2019, @11:37AM (1 child)

        by pTamok (3042) on Sunday March 03 2019, @11:37AM (#809386)

        BAHINMYDEFENCEIAMFO
        LLOWINGTHEPRECENTOFC
        LASSICALWRITINGWHICHD
        IDNOTUSEPUNCTUATIONO
        RSPACESANDDIDNOTEVE
        NSPILTLINESATWORDBOU
        NDARIES [wikipedia.org]

        Luckily, Unicode does not support the mirroring of individual characters, so I can't write Boustrophedonic [wikipedia.org] text correctly.

  • (Score: 0) by Anonymous Coward on Saturday March 02 2019, @11:12PM (1 child)

    by Anonymous Coward on Saturday March 02 2019, @11:12PM (#809268)

    According to some onahole sales material I once read, some water tanks are lined with silver for this reason.

  • (Score: 2) by fritsd on Sunday March 03 2019, @01:14PM (1 child)

    by fritsd (4586) on Sunday March 03 2019, @01:14PM (#809401) Journal

    I once saw an advertisement for silver underpants.

    I'm quite sure it wasn't a joke.

    IIRC it wasn't chain mail, but knitted with thin silver wire or something.

    • (Score: 0) by Anonymous Coward on Monday March 04 2019, @06:14AM

      by Anonymous Coward on Monday March 04 2019, @06:14AM (#809713)

      Clothing on the space station contains silver. It is single-use, worn for weeks.

  • (Score: 2) by realDonaldTrump on Monday March 04 2019, @02:11AM

    by realDonaldTrump (6614) on Monday March 04 2019, @02:11AM (#809652) Homepage Journal

    We love gold the best, don't we? I went with gold & marble for my apartment. And I'm very happy I did. I get so many compliments about it. Everybody says it looks like a million bucks. In fact, it was much more than that.

    I'll tell you, it wasn't always gold & marble. Originally we went with Angelo Donghia (who died w/AIDS, RIP!!) for the interior. This guy did work for Calvin Klein, Ralph Lauren, Mary Tyler Moore, Liza Minelli. Halston, Diana Ross -- everybody was telling us what a great guy he was. So we let him do his thing. But it was too much grey Flannel. I'm talking wall to wall and floor to ceiling grey. People would come to the apartment, they'd be all, "oh, I'll get it looks like rain!" So we ripped out all that junk. And brought in Henry Conversano, the best casino guy. Who designed the Golden Nugget in Atlantic City. And he put in the gold & marble -- in the very special style of Louis XIV, famous and classy King from France. It's not Louis XIV, it's inspired. Sometimes referred to as reproduction. Looks the same except it's brand new. And by the way, costs much less. Magnificent!!!

  • (Score: 0) by Anonymous Coward on Monday March 04 2019, @06:17AM

    by Anonymous Coward on Monday March 04 2019, @06:17AM (#809714)

    You don't need much roentgenium to kill all the bacteria. Just a thin coating of a dilute solution containing roentgenium is enough to kill everything, largely due to the 100-second half life and resulting radiation.