Submitted via IRC for Bytram
The findings, published this week in Nature Communications, suggest that, although heavy drinking is a prerequisite for AUD, variants in several genes -- DRD2 and SIX3, for example -- may need to be present for people to develop AUD.
"This study has revealed an important genetic independence of these two traits that we haven't seen as clearly before," said Henry R. Kranzler, MD, a professor of Psychiatry in the Perelman School of Medicine at the University of Pennsylvania, and first author of the study. "Focusing on variants only linked to AUD may help identify people at risk and find targets for the development of medications to treat it. The same applies to alcohol consumption, as those variants could inform interventions to help reduce consumption in heavy drinkers, who face their own set of adverse effects."
[...] Environmental, hereditary, and genetic factors all play a role in AUD; however, many of the variants across the genome believed to be associated with the disorder remain to be identified.
For the study, the researchers used genetic data from the multi-ethnic Million Veteran Program (MVP), a national, voluntary research program sponsored by the Department of Veterans Affairs, which includes white, African-American, Latino, and Asian participants. The diverse study sample is notable, in that it included more than 50,000 African-Americans, one of the largest genome-wide studies of this population. Scores from the Alcohol Use Disorder Identification Test-Consumption (AUDIT-C) screenings and AUD diagnoses were obtained from the same population (a total of 274,424 people) to conduct the GWAS for the two traits. The researchers also analyzed other data from health records to look for correlations between genes and diseases, as well as other non-alcohol related traits.
(Score: 1) by DECbot on Friday April 05 2019, @12:20AM (2 children)
Thanks
Sometimes I wonder if people still get the reference.
cats~$ sudo chown -R us /home/base
(Score: 2) by Magic Oddball on Friday April 05 2019, @05:47AM
I recognized it right away; I'd be surprised if anyone who was 12-30 and online back in 2000 wouldn't.
(Score: 0) by Anonymous Coward on Friday April 05 2019, @10:33PM
But, but, it's not presented to me as a link so I can see what it means. And Google doesn't provide any relevant hits, nor does unix.stackexchange.com. Forcing me to use my brain to parse that command line. I hate you!
More seriously, if you *really* want it to be "All your base," shouldn't you do something like:
cats~$ sudo chown -R us `find /home -type d -name [Bb][Aa][Ss][Ee]`
BTW, I'm full of good ideas like that! i can give you tips on flossing, grooming your pets and making your relationships more satisfying. When do I start?