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posted by chromas on Wednesday April 17 2019, @12:57AM   Printer-friendly
from the No,-I'm-storing-up-potential-iPSCs dept.

According to an article in the journal Advanced Science, researchers at Tel Aviv University were able to create a small 3D-printed heart that included blood vessels out of human tissue.

Until now, researchers have only been able to print simple tissues lacking blood vessels, so a 3D, fully vascularized engineered heart is a step in the right direction.

The process consists of taking a sample of abdominal fat tissue, reprogramming the cells to become induced pluripotent stem cells (iPSCs), differentiating these into cardiac muscle cells and blood vessel cells, and combining them with hydrogels to form structures for the cells to proliferate on.

Heart disease causes one in four deaths in the US (about 610,000 people a year), and there's a shortage of heart donors for transplants, so 3D-printed hearts could help solve a major issue

As a next step, the team plans to culture, print, and transplant similar hearts into animals. Significant challenges still remain, such as the efficient cultivation of the stem cells to gain the large quantity needed to engineer full-size organs and improvement of the blood vessel network demonstrated; the team indicates we are many, many years from from doing this for humans.


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  • (Score: 2) by Pslytely Psycho on Wednesday April 17 2019, @02:17AM (3 children)

    by Pslytely Psycho (1218) on Wednesday April 17 2019, @02:17AM (#830786)

    https://onlinelibrary.wiley.com/doi/full/10.1002/advs.201900344 [wiley.com]

    " Wab grown wabbit hearts! Oh, dat's gonna make dat wascally wabbit much harder to kill " - Elmer Fudd

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    Alex Jones lawyer inspires new TV series: CSI Moron Division.
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  • (Score: 2) by takyon on Wednesday April 17 2019, @02:26AM (2 children)

    by takyon (881) <takyonNO@SPAMsoylentnews.org> on Wednesday April 17 2019, @02:26AM (#830788) Journal

    That's the first link in TFS.

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    • (Score: 2) by MostCynical on Wednesday April 17 2019, @02:57AM

      by MostCynical (2589) on Wednesday April 17 2019, @02:57AM (#830798) Journal

      You expect close reading of TFS, now? Most people barely make it past the headline.

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    • (Score: 2) by Pslytely Psycho on Wednesday April 17 2019, @04:59AM

      by Pslytely Psycho (1218) on Wednesday April 17 2019, @04:59AM (#830833)

      Huh, so it is. I couldn't get that page to open earlier. I didn't notice I linked to the same page a few hour later.
      Meh, if that's the worst I do today, it will be a good day.

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      Alex Jones lawyer inspires new TV series: CSI Moron Division.