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posted by chromas on Saturday April 20 2019, @12:40AM   Printer-friendly
from the C10H19N2 dept.

Nicotine Replacement: When Quitting Cigarettes, Consider Using More Nicotine, Not Less:

When delivered through cigarettes, nicotine is considered to be one of the most addictive substances on Earth, so it may seem odd to suggest that people should use more, rather than less, to quit smoking. A recent review of the research, however, has found just that.

Nicotine replacement therapy, known as NRT, has been used to help people safely quit smoking for more than 20 years. It can be prescribed by a doctor but, in many countries, is also available to buy from grocery stores and pharmacies. The Cochrane review (Cochrane assesses evidence on healthcare interventions and summarises the findings) looked at the best ways to use NRT to quit smoking – and found three ways in which using more nicotine might help:

  1. Use two forms of NRT rather than one. [...]
  2. Start to use NRT before stopping smoking. [...]
  3. Higher doses of NRT may help some people.

If you don't get a "happy" jolt from the release of dopamine (because the levels of nicotine never dropped to a stage of craving), the perceived "reward" for smoking is reduced/removed.


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  • (Score: 2) by JoeMerchant on Saturday April 20 2019, @02:25AM

    by JoeMerchant (3937) on Saturday April 20 2019, @02:25AM (#832418)

    Some researchers were studying how light/dark patterns affect mouse sleep cycles. They built a big, like 6x6, experimental cage setup and controlled the lighting in each enclosure - measuring the occupant's sleep wake patterns. They had all kinds of light dark patterns, mostly on 24 hour cycles. The one graph that stood out for me was a mouse that was exposed to 10 minutes of light followed by 23:50 of dark - after a few days, that mouse settled on a pattern where it would fall asleep almost immediately after the light pulse, slept a normal-ish 10 hours, then would wake up and do it all over again - basically put to sleep by the falling edge of the light pulse.

    If you're trying to quit nicotine, it might make sense to get a good solid hit of it before switching off altogether - kind of like ripping off the bandage all at once, rather than drawing it out a little at a time.

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