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posted by chromas on Friday June 21 2019, @08:48PM   Printer-friendly
from the https://www.youtube.com/watch?v=gaFh71YwZ4Y dept.

Submitted via IRC for Bytram

Early and regular cannabis use by youth is associated with alteration in brain circuits that support cognitive control

The development of neural circuits in youth, at a particularly important time in their lives, can be heavily influenced by external factors -- specifically the frequent and regular use of cannabis. A new study [...] reports that alterations in cognitive control -- an ensemble of processes by which the mind governs, regulates and guides behaviors, impulses, and decision-making based on goals are directly affected.

[...] The findings are based on functional magnetic resonance imaging (fMRI) data acquired from 28 adolescents and young adults (aged 14-23 years) with significant cannabis use and 32 age and sex-matched non-using healthy controls. Participants were scanned during their performance of a Simon Spatial Incompatibility Task, a cognitive control task that requires resolving cognitive conflict to respond accurately.

Compared to their healthy counterparts, the adolescents and young adults with significant cannabis use showed reduced activation in the frontostriatal circuits that support cognitive control and conflict resolution.

The authors also examined the degree to which fluctuations in activity in relation to conflict resolution is synchronized across the different regions comprised in this frontostriatal circuit (that is, to what extent are regions functionally connected with each other). Although circuit connectivity did not differ between cannabis-using and non-using youth, the research team found an association between how early individuals began regularly using cannabis and the extent to which frontostriatal regions were disrupted, suggesting that earlier chronic use may have a larger impact on circuit development than use of later onset.

Deficient Functioning of Frontostriatal Circuits During the Resolution of Cognitive Conflict in Cannabis-Using Youth (DOI: 10.1016/j.jaac.2018.09.436)


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  • (Score: 2) by JoeMerchant on Saturday June 22 2019, @03:08AM (3 children)

    by JoeMerchant (3937) on Saturday June 22 2019, @03:08AM (#858752)

    Alcohol messes with more than brain development, it screws up physical development as well.

    The truth of the matter is that we barely know anything about the real, total effects of any chemicals on anybody - not long-term, not really. We've barely started cataloging carcinogens, and can't yet make up our minds about things like glycophosphates. It just gets so much more dramatic if you're dosing organisms (and people are organisms) during development, since it can introduce developmental changes which last a lifetime.

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  • (Score: 2) by NotSanguine on Saturday June 22 2019, @04:01AM

    Alcohol messes with more than brain development, it screws up physical development as well.

    The truth of the matter is that we barely know anything about the real, total effects of any chemicals on anybody - not long-term, not really. We've barely started cataloging carcinogens, and can't yet make up our minds about things like glycophosphates. It just gets so much more dramatic if you're dosing organisms (and people are organisms) during development, since it can introduce developmental changes which last a lifetime.

    You won't get any argument about that from me.

    And knowledge that mind-altering substances (be it alcohol or anything else) can have negative physical and mental effects is nothing new either. Not that such knowledge has ever stopped anyone.

    What's more, it shouldn't be a reason to ban those substances either, IMHO.

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  • (Score: 1) by fustakrakich on Saturday June 22 2019, @06:06AM (1 child)

    by fustakrakich (6150) on Saturday June 22 2019, @06:06AM (#858786) Journal

    It just gets so much more dramatic if you're dosing organisms (and people are organisms) during development, since it can introduce developmental changes which last a lifetime.

    All lies, spread by the Establishment [soylentnews.org]!

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    • (Score: 2) by JoeMerchant on Saturday June 22 2019, @11:25AM

      by JoeMerchant (3937) on Saturday June 22 2019, @11:25AM (#858808)

      Dramatic isn't necessarily bad.

      What does blow me away is how we take something like MJ which has a relatively long track record of relatively little serious or permanent harm and we ban it from all use, but we turn around and feed our newborns formula made from all kinds of experimental shit and then push out commercial campaigns (1950s through early 1990s) trying to make women feel uncomfortable about breastfeeding their newborns so the manufacturers can sell more formula and associated products.

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