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Why people gain weight as they get older
The scientists studied the fat cells in 54 men and women over an average period of 13 years. In that time, all subjects, regardless of whether they gained or lost weight, showed decreases in lipid turnover in the fat tissue, that is the rate at which lipid (or fat) in the fat cells is removed and stored. Those who didn't compensate for that by eating less calories gained weight by an average of 20 percent, according to the study which was done in collaboration with researchers at Uppsala University in Sweden and University of Lyon in France.
The researchers also examined lipid turnover in 41 women who underwent bariatric surgery and how the lipid turnover rate affected their ability to keep the weight off four to seven years after surgery. The result showed that only those who had a low rate before the surgery managed to increase their lipid turnover and maintain their weight loss. The researchers believe these people may have had more room to increase their lipid turnover than those who already had a high-level pre-surgery.
"The results indicate for the first time that processes in our fat tissue regulate changes in body weight during ageing in a way that is independent of other factors," says Peter Arner, professor at the Department of Medicine in Huddinge at Karolinska Institutet and one of the study's main authors. "This could open up new ways to treat obesity."
Prior studies have shown that one way to speed up the lipid turnover in the fat tissue is to exercise more. This new research supports that notion and further indicates that the long-term result of weight-loss surgery would improve if combined with increased physical activity.
"Obesity and obesity-related diseases have become a global problem," says Kirsty Spalding, senior researcher at the Department of Cell and Molecular Biology at Karolinska Institutet and another of the study's main authors. "Understanding lipid dynamics and what regulates the size of the fat mass in humans has never been more relevant."
P. Arner, et.al. Adipose lipid turnover and long-term changes in body weight. Nature Medicine, 2019; 25 (9): 1385 DOI: 10.1038/s41591-019-0565-5
(Score: 2, Informative) by Anonymous Coward on Tuesday September 10 2019, @01:40PM (3 children)
What they’re saying is that to keep from gaining weight, as we age we need to eat less and move more.
(Score: 4, Informative) by All Your Lawn Are Belong To Us on Tuesday September 10 2019, @02:28PM
True, so long as one continues to intake adequate nutrition. We forget in our land of obesity that for the elderly the opposite can happen and anxorexia can develop. Not as common but it can.
This sig for rent.
(Score: 2, Insightful) by Anonymous Coward on Tuesday September 10 2019, @03:55PM (1 child)
It's the "move more" part that's so difficult. Worn knees and ankles make it difficult to move around so much. Then, there is a vicious circle - you gain the first couple pounds, which makes it harder to move, which leads to a couple more pounds, and so on.
(Score: 2) by c0lo on Tuesday September 10 2019, @10:00PM
Hit the swimming pool (or the seaside if available).
At the worst, you may evolve into a whale, but sure thing you won't complain about knees or ankles.
https://www.youtube.com/watch?v=aoFiw2jMy-0 https://soylentnews.org/~MichaelDavidCrawford