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posted by Fnord666 on Tuesday October 29 2019, @02:56PM   Printer-friendly
from the fun-with-psychedelics dept.

Submitted via IRC for soylent_red

Recent years have seen a renewed interest in the clinical application of classic psychedelics in the treatment of depression and anxiety disorders. Researchers of the University of Zurich have now shown that mindfulness meditation can enhance the positive long-term effects of a single dose of psilocybin, which is found in certain mushrooms.

[...] Researchers at the University Hospital of Psychiatry Zurich have now for the first time examined the potential synergistic effects of combining mindfulness meditation and psilocybin. The scientists recruited 40 meditation experts who were taking part in a five-day mindfulness retreat. In the double-blind study, the participants were administered either a single dose of psilocybin or a placebo on the fourth day of the group retreat. Using various psychometric and neurocognitive measurements, the team of researchers were able to show that mindfulness meditation increased the positive effects of psilocybin, while counteracting possible dysphoric responses to the psychedelic experience. "Psilocybin markedly increased the incidence and intensity of self-transcendence virtually without inducing any anxiety compared to participants who received the placebo," says first author Lukasz Smigielski, who conducted the study directed by UZH professor of psychiatry Franz Vollenweider.

[...] "Our findings shed light on the interplay between pharmacological and extra-pharmacological factors in psychedelic states of mind," says Vollenweider. "They indicate that mindfulness training enhances the positive effects of a single dose of psilocybin, and can increase empathy and permanently reduce ego-centricity. This opens up new therapeutic avenues, for example for the treatment of depression, which is often accompanied by increased self-focus and social deficits."

Source: https://www.sciencedaily.com/releases/2019/10/191024075003.htm

Journal Reference: Lukasz Smigielski, Michael Kometer, Milan Scheidegger, Rainer Krähenmann, Theo Huber, Franz X. Vollenweider. Characterization and prediction of acute and sustained response to psychedelic psilocybin in a mindfulness group retreat. Scientific Reports, 2019; 9 (1) DOI: 10.1038/s41598-019-50612-3


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  • (Score: 1, Informative) by Anonymous Coward on Tuesday October 29 2019, @06:04PM (2 children)

    by Anonymous Coward on Tuesday October 29 2019, @06:04PM (#913364)

    Depends on the church!!

      This little book seems to have slipped through the cracks, but it's an excellent guide for anyone so inclined, "Start your own religion" by Tim Leary, here's the first link I found with the text, I seem to remember that the printed book had some illustrations(?)
    http://www.leary.ru/download/leary/Timothy%20Leary%20-%20Start%20Your%20Own%20Religion.pdf [leary.ru] (pdf)

    When the individual's behaviour and consciousness get hooked to a routine sequence of external actions, he is a dead robot, and it is time for him to die and be reborn. Time to "Drop-out", "Turn-on", and "Tune-in". This period of robotisation is called the Kali Yuga, the Age of Strife and Empire, the peak of so called civilisation, the Johnson Administration, etc. This relentless law of Death, Life, Change is the rhythm of the galaxies and the seasons; the rhythm of the seed. It never stops.

    ...

    When you Turn-on remember: you are not a naughty boy, getting high for kicks. You are a spiritual voyager furthering the most ancient, noble quest of man. When you Turn-on you shed the fake-prop TV studio and costume and join the holy dance of the visionaries. You leave LBJ and Bob Hope; you join Lao Tse, Christ, Blake.
    Never underestimate the sacred meaning of the Turn-on. To Turn-on you need a sacrament. A sacrament is a visible external thing which turns the key to the inner doors. A sacrament must bring about bodily changes. A sacrament flips you out of the TV-studio game and harnesses you to the two billion-year-old flow inside.
    A sacrament which works is dangerous to the establishment which runs the fake-prop TV-studio - and to that part of your mind which is hooked to the studio game. Each TV-prop society produces exactly that body-changing sacrament which will flip out the mind of the society.
    Today the sacrament is LSD. New sacraments are coming along. Sacraments wear out. They become part of the social TV studio game. Treasure LSD while it still works. In fifteen years it will be tame, socialised, and routine.

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  • (Score: 0) by Anonymous Coward on Tuesday October 29 2019, @06:16PM (1 child)

    by Anonymous Coward on Tuesday October 29 2019, @06:16PM (#913369)

    In fifteen years it will be tame, socialised, and routine.

    He was optimistic about that part.

    Most people don't have access to LSD, and there are dozens of similar but distinct analogues of the chemical being sold as LSD. Just like with all the fake MDMA and other fake drugs. That's neither tame, socialised, nor routine.

    • (Score: 1, Interesting) by Anonymous Coward on Tuesday October 29 2019, @06:49PM

      by Anonymous Coward on Tuesday October 29 2019, @06:49PM (#913376)

      > That's neither tame, socialised, nor routine.

      Wooosh!

      You missed the whole point. These days, mindfulness training might well be the sacrament of choice. It's a moving target, as soon as one goes mainstream it loses it's effect (or as you note, poor copies are the only versions available) and you need to find something new.

      Met Leary a couple of times in the late 1980s in LA through a friend. He was razor sharp, very much doing his own thinking. At that time he was converting a "personality test" (for lack of a better term) into a computer game...in hopes that it might be the next thing, for awhile.