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Immune discovery 'may treat all cancer'
A newly-discovered part of our immune system could be harnessed to treat all cancers, say scientists.
The Cardiff University team discovered a method of killing prostate, breast, lung and other cancers in lab tests.
The findings, published in Nature Immunology, have not been tested in patients, but the researchers say they have "enormous potential".
Experts said that although the work was still at an early stage, it was very exciting.
Also at Cardiff University:
Cardiff researchers have now discovered T-cells equipped with a new type of T-cell receptor (TCR) which recognises and kills most human cancer types, while ignoring healthy cells.
[...] [The] Cardiff study, published today in Nature Immunology, describes a unique TCR that can recognise many types of cancer via a single [human leukocyte antigen (HLA)]-like molecule called MR1.
Unlike HLA, MR1 does not vary in the human population - meaning it is a hugely attractive new target for immunotherapies.
Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1 (DOI: 10.1038/s41590-019-0578-8) (DX)
(Score: 2) by pdfernhout on Friday January 24 2020, @01:49AM (1 child)
https://en.wikipedia.org/wiki/Linus_Pauling#Death_and_legacy [wikipedia.org]
"Pauling died of prostate cancer on August 19, 1994, at 19:20 at home in Big Sur, California. He was 93 years old."
VItamin C status can be seen in part as a marker for how diverse your diet it and how many fruits and veggies you eat. Better advice on preventing (and sometimes treating) cancer is to eat "G-BOMBS":
https://www.drfuhrman.com/elearning/eat-to-live-blog/62/the-healthiest-anti-cancer-foods-g-bombs [drfuhrman.com]
"”G-BOMBS” [Greens, Beans, Onions, Mushrooms, Berries, Seeds] is an acronym that you can use to remember the best anti-cancer, health-promoting foods on the planet. These are the foods that you should eat every day, making up a significant proportion of your diet. They are extremely effective at preventing chronic disease, including cancer and promoting health and longevity."
The biggest challenge of the 21st century: the irony of technologies of abundance used by scarcity-minded people.
(Score: 0) by Anonymous Coward on Friday January 24 2020, @03:19AM
That may or may not be helpful but large amounts of vitamin C are impossible to get via diet. How much would you need to eat to get only 10 grams per day?