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posted by martyb on Tuesday March 03 2020, @05:42PM   Printer-friendly
from the How-old-is-Betteridge? dept.

Is Aging a Disease?

Whether ageing can be cured or not, there are arguments for thinking about it like a disease. But there are major pitfalls, too.

The first depiction of humanity's obsession with curing death is The Epic of Gilgamesh—which, dating back to at least 1800 B.C., is also one of the first recorded works of literature, period. Centuries later, the ancient Roman playwright Terentius declared, "Old age itself is a sickness," and Cicero argued "we must struggle against [old age], as against a disease." In 450 B.C., Herodotus wrote about the fountain of youth, a restorative spring that reverses aging and inspired explorers such as Ponce de León. But what once was a mythical holy grail is now seemingly within tantalizing reach. As humans' understanding and knowledge of science and technology have increased, so too have our life spans.

[...] Maybe the ancients weren't wrong, and aging can be not only delayed but cured like a disease. Over the years, the movement to classify aging as a disease has gained momentum not only from longevity enthusiasts but also from scientists. In 1954, Robert M. Perlman published a paper in the Journal of American Geriatrics Society called "The Aging Syndrome" in which he called aging a "disease complex." Since then, others have jumped on board, including gerontologists frustrated by a lack of funding to study the aging process itself.

[...] However, labeling aging itself as a disease is both misleading and detrimental. Pathologizing a universal process makes it seem toxic. In our youth-obsessed society, ageism already runs rampant in Hollywood, the job market, and even presidential races. And calling aging a disease doesn't address critical questions about why we age in the first place. Instead of calling aging a disease, scientists should aim to identify and treat the underlying processes that cause aging and age-related cellular deterioration.

Medical understanding of that cellular deterioration began in 1962, when Leonard Hayflick, professor of anatomy at the University of California San Francisco School of Medicine, made fundamental breakthroughs to understanding aging: He discovered a limit to how many times typical human cells divide before they become senescent, or exhausted. Before then, scientists had assumed human cells were immortal. Hayflick also figured out that telomeres, which cap the ends of chromosomes and prevent them from fraying, much like plastic tips preserve the ends of shoelaces, shorten each time a cell divides. When the telomeres get short enough, a cell stops dividing.

[...] Many gerontologists distinguish between "health span" and "life span," the length of time someone enjoys relative good health versus the length of someone's life. Longevity while in poor health, pain, or with limitations that sap quality of life makes little sense. Fleming urges "regulators and public policy makers to embrace healthspan as an organizing focus for facilitating the development of medicine that target aging and chronic diseases." This shift would promote research on disease-causing processes, which could help us prevent more age-related diseases, not just manage them.

As gerontologists Sean Leng and Brian Kennedy put it, "Aging is the climate change of health care." The Population Reference Bureau predicts that 100 million Americans will be 65 or older by 2060. How will we care for this population? It's daunting to think about one's own aging, let alone the 16 percent of the world's population who will be seniors[sic] citizens by midcentury. A big-picture approach focused on the processes of aging—processes we share with nearly all living organisms—will put us on a path not only to longer lives but to healthier ones.


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  • (Score: 2, Disagree) by barbara hudson on Wednesday March 04 2020, @12:55AM (5 children)

    by barbara hudson (6443) <barbara.Jane.hudson@icloud.com> on Wednesday March 04 2020, @12:55AM (#966271) Journal
    Why is anyone afraid of having their address posted online? Nobody is going to mail you an envelope with ricin powdered in it or anything.

    we used to have things called phone books with your name and address in it. Nobody cared.

    I've posted my address in discussions both here and on the geeen site, using my legal name, the world didn't come to an end.

    Did the Internet turn everyone into cowards afraid of bogeymen? As you pointed out, you're retired, you can't be fired. So what gives?

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  • (Score: 2) by Azuma Hazuki on Wednesday March 04 2020, @02:55AM (2 children)

    by Azuma Hazuki (5086) on Wednesday March 04 2020, @02:55AM (#966310) Journal

    I will never understand how unafraid you are of that. In your position I'd be goddamn terrified, not because someone would mail me something, but because they might, I don't know, shoot the place up or set it on fire? Stuff like that.

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    • (Score: 2) by barbara hudson on Wednesday March 04 2020, @04:56AM (1 child)

      by barbara hudson (6443) <barbara.Jane.hudson@icloud.com> on Wednesday March 04 2020, @04:56AM (#966355) Journal

      Well, people weren't doing that in pre-Internet days when phone books were in every home, so the only thing that's changed is the internet gives people more ability to be stirred up on hate subjects. But those same people are too afraid to do anything in real life. Keyboard warriors indeed.

      The colder weather helps. Violent behaviour goes down with temperature. It's harder to spontaneously go out and do something stupid when you have to bundle up in boots, coat, gloves, hat, clean off the car, defrost the windows, navigate icy streets, all so you can punch someone in the face. Hard to throw punches if you're wearing multiple layers of clothing and a parka.

      And during heat waves people tend to stay in places with ac. Spring, people are just happy to see winter start to go, and fall - well, we didn't have one this year.

      Which is why Asia Bibi was stupid to publicly complain that she was hiding in Canada in a city without 4 seasons and only snow, snow, snow. Easy to figure out the government stashed her and her husband in Montreal. Anyway,she wants to get asylum in France when her 1 year refugee visa is up, and considering how many other countries were afraid that taking her in would make them a terrorists target, that we've been feeding, clothing , and sheltering her at taxpayer expense , as well as providing security, she seems a bit ungrateful, so no loss there.

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      • (Score: 0) by Anonymous Coward on Wednesday March 04 2020, @03:28PM

        by Anonymous Coward on Wednesday March 04 2020, @03:28PM (#966490)

        Phone books were just any index of numbers and nobody wants to be in one these days to to abuse.

        Three internet is different, people often post personal things and get in arguments. People lose jobs over things that happen online. If you don't understand why it's important to maintain some separation, it's because you haven't been paying attention.

  • (Score: 0) by Anonymous Coward on Wednesday March 04 2020, @12:20PM (1 child)

    by Anonymous Coward on Wednesday March 04 2020, @12:20PM (#966437)

    Clearly you've never been stalked, randomly selected for targeted fraud, or been part of a group subject to McCarthism style tactics. Just because you ignore reality doesn't mean other people don't take their own security for granted.

    • (Score: 2) by barbara hudson on Wednesday March 04 2020, @05:04PM

      by barbara hudson (6443) <barbara.Jane.hudson@icloud.com> on Wednesday March 04 2020, @05:04PM (#966541) Journal

      Clearly you've never been stalked, randomly selected for targeted fraud, or been part of a group subject to McCarthism -

      I've been stalked both by trans-haters and by trans-fans. And by guys just looking for a piece of ass who won't take no for an answer. I've been assaulted, sexually harassed, sexually assaulted, and NOT ONE OF THEM NEEDED MY ADDRESS. Studies show that people are a poor judge of risk. You obviously are in that group if you think that someone having your address will make you more likely to be harassed , assaulted, etc.

      No wonder you post as a coward. You are one.

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