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posted by martyb on Thursday April 16 2020, @10:52PM   Printer-friendly
from the Smoke-'em-if-you-got-'em? dept.

We received three different submissions pertaining to the effects of smoking on COVID-19. One study suggests that those who smoke have a reduced likelihood of hospitalization. The comingling of separate data for male and female patients and analysis based on that data seems unusual to me. The second report is not restricted to hospitalizations, but only to those who tested positive for the virus. Their results also suggested a lessened number of self-identified smokers than smoking rates in the general public would suggest. The third and final story submission introduced vaping to the discussion, and comes to the opposite conclusion in suggesting that smoking or vaping may increase the risk of contracting COVID-19.

Confounding these analyses is that all reports of smoking are self-reported. I can well imagine if someone had tried to quit smoking, and had convinced their spouse they had indeed stayed stopped, they would be reluctant to reveal in their spouse's presence that they were a smoker. If anything, though, would that not run counter to the possibility of a protective effect? As with most things pertaining to the virus, it is likely too early to tell for certain, but it does add another dimension to the discussion. Assuming that smoking does have a preventative effect, what could be the cause? Increased residue in the lungs makes it harder for the virus to latch onto the lung's cells and infect? Could it be that chemicals in the smoke serve to impair the virus's ability to survive in the lungs and cause an infection?

Study: Smokers Appear Less Likely to be Hospitalised with COVID-19

https://www.breitbart.com/europe/2020/04/02/study-smokers-less-likely-to-be-hospitalised-with-covid-19/:

Smoking may reduce the likelihood of being hospitalised with coronavirus, claims a study.

Here is the abstract of the studySmoking, vaping and hospitalization for COVID-19 – by researchers at the University of West Attica in Greece and New York University.

The study presents an analysis of the current smoking prevalence among hospitalized patients with COVID-19 in China, compared to the population smoking prevalence in China (52.1% in males and 2.7% in females). Through a systematic research of the literature (PubMed) we identified 7 studies examining the clinical characteristics of a total of 2352 hospitalized COVID-19 patients that presented data on the smoking status.

The expected number of smokers was calculated using the formula Expected smokers = (males x 0.521) + (females x 0.027). An unusually low prevalence of current smoking was observed among hospitalized COVID-19 patients (8.7%, 95%CI: 7.6-9.9%) compared to the expected prevalence based on smoking prevalence in China (30.3%, 95%CI: 28.4-32.1%; z-statistic: 22.80, P < 0.0001). This preliminary analysis does not support the argument that current smoking is a risk factor for hospitalization for COVID-19, and might even suggest a protective role.

The latter could be linked to the down-regulation of ACE2 expression that has been previously known to be induced by smoking. However, other confounding factors need to be considered and the accuracy of the recorded smoking status needs to be determined before making any firm conclusions. As a result, the generalized advice on quitting smoking as a measure to improve health risk remains valid, but no recommendation can currently be made concerning the effects of smoking on the risk of hospitalization for COVID-19.

No studies recording e-cigarette use status among hospitalized COVID-19 patients were identified. Thus, no recommendation can be made for e-cigarette users.

Does smoking PROTECT against coronavirus?

https://www.dailymail.co.uk/news/article-8214749/David-Hockney-claims-smoking-cigarettes-PROTECT-against-coronavirus.html:

When world-famous artist David Hockney wrote a letter to the Daily Mail saying he believes smoking could protect people against the coronavirus many scoffed.

Mr Hockney wrote: 'Could it not be that smokers have developed an immune system to this virus? With all these figures coming out, it's beginning to look like that to me.'

Understandably the claim was brushed off as laughable and 'rubbish' by many.

But is it?

A leading infectious disease expert at University College London, Professor Francois Balloux, said there is 'bizarrely strong' evidence it could be true.

And data from multiple Chinese studies shows that COVID-19 hospital patients contained a smaller proportion of smokers than the general population (6.5 per cent compared to 26.6 per cent), suggesting they were less likely to end up in hospital.

Another study, by America's Centers for Disease Control of over 7,000 people who tested positive for coronavirus, found that just 1.3 per cent of them were smokers - against the 14 per cent of all Americans that the CDC says smoke.

The study also found that the smokers stood no greater chance of ending up in hospital or an ICU.

The reasons for this are unclear.

FDA Shifts Its Covid-19 Stance on Vaping, Smoking Impact

https://www.msn.com/en-us/news/technology/fda-shifts-its-covid-19-stance-on-vaping-smoking-impact/ar-BB12HeLc:

(Bloomberg) -- The U.S. Food and Drug Administration modified its stance on Covid-19 and vaping, saying it has an unknown effect on the risk of the new coronavirus, while warning that smoking can create worse outcomes.

"E-cigarette use can expose the lungs to toxic chemicals, but whether those exposures increase the risk of Covid-19 is not known," the agency said Wednesday in an emailed response to a question from Bloomberg News.

The agency had said late last month that vapers and smokers with underlying health conditions might be at higher risk from complications.

Its description of cigarettes' risks also differed from its earlier statements. "Cigarette smoking causes heart and lung diseases, suppresses the immune system, and increases the risk of respiratory infections," FDA spokeswoman Alison Hunt said. "People who smoke cigarettes may be at increased risk from Covid-19, and may have worse outcomes from Covid-19."


Original Submission #1Original Submission #2Original Submission #3

 
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  • (Score: 4, Interesting) by HiThere on Thursday April 16 2020, @11:55PM (4 children)

    by HiThere (866) Subscriber Badge on Thursday April 16 2020, @11:55PM (#983856) Journal

    As for lower hospitalization, I've got a guess. Smokers don't want to go into a place where they aren't allowed to smoke, so they stay home until they either die or recover.

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  • (Score: 3, Interesting) by The Mighty Buzzard on Friday April 17 2020, @03:30AM (3 children)

    Does China even bar smoking in hospitals? Me, I'm thinking smoking may actually chemically inhibit the virus. There are very strong indications it's interfering with our homogoblins (Yes, I know it's hemoglobin. It's more fun to say though.) and so do many things in a cigarette; them getting in each others' way is entirely plausible.

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    • (Score: 1, Interesting) by Anonymous Coward on Friday April 17 2020, @04:28AM

      by Anonymous Coward on Friday April 17 2020, @04:28AM (#983974)

      That sort of fits with the ventilators-are-useless-its-destroying-hemoglobin hypothesis. Smokers usually have a significant (but not incapacitating) percentage of carbon monoxide in their blood. It might bind to hemoglobin strongly enough to exclude the virus. As that CO is slowly removed from patients on ventilators it provides a small source of undamaged hemoglobin. This might be enough to 'flatten the curve' and keep them alive until their immune system beats the virus and their bone marrow can replace the blood cells.
      They possibly also have a higher hemoglobin baseline anyway, just because their bodies have adapted to a CO rich, damaged lung environment.

    • (Score: 2) by HiThere on Friday April 17 2020, @03:32PM (1 child)

      by HiThere (866) Subscriber Badge on Friday April 17 2020, @03:32PM (#984142) Journal

      I've no idea. I'm rather certain, however, that everywhere bans smoking while you're on Oxygen. And certainly in China there was, at least at the height of the epidemic, lots of other reasons to avoid a hospital, but I can't imagine that they allow smoking near people who are on oxygen

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      • (Score: 3, Interesting) by The Mighty Buzzard on Saturday April 18 2020, @05:49PM

        by The Mighty Buzzard (18) Subscriber Badge <themightybuzzard@proton.me> on Saturday April 18 2020, @05:49PM (#984617) Homepage Journal

        I wouldn't bet on it. Oxygen and cigarettes ain't as dangerous a combination as you seem to think. My granddad smoked with a pure oxygen rig up his nose for years and never had a mishap. Even took the tubes out of his nose and blew them on a lit cigarette once when I suggested it might be a bad idea. The result was extremely boring.

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