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posted by Fnord666 on Friday April 17 2020, @11:49AM   Printer-friendly
from the my-switch-has-a-short dept.

Arthur T Knackerbracket has found the following story:

Scientists may have solved one of the most puzzling and persistent mysteries in neuroscience: why some people are "right-brained" while others are "left-brained."

The answer lies in how certain genes on each side of the brain are switched "on" and "off" through a process called epigenetic regulation. The findings may explain why Parkinson's disease and other neurological disorders frequently affect one side of the body first, a revelation that has far-reaching implications for development of potential future treatments.

The study was led by Van Andel Institute's Viviane Labrie, Ph.D., and published in the journal Genome Biology.

"The mechanisms underlying brain asymmetry have been an elephant in the room for decades," Labrie said. "It's thrilling to finally uncover its cause, particularly given its potential for helping us better understand and, hopefully one day, better treat diseases like Parkinson's."

[...] The findings also give scientists a vital window into the various biological pathways that contribute to symptom asymmetry in Parkinson's, including brain cell development, immune function and cellular communication.

"We all start out with prominent differences between the left and right sides of our brains. As we age, however, our hemispheres become more epigenetically similar. For Parkinson's, this is significant: people whose hemispheres are more alike early in life experienced faster disease progression, while people whose hemispheres were more asymmetric had slower disease progression," Labrie said. "Many of these changes are clustered around genes known to impact Parkinson's risk. There is huge potential to translate these findings into new therapeutic strategies."

Labrie is already starting to look at this phenomenon in other neurological diseases like Alzheimer's.

Peipei Li, Elizabeth Ensink, Sean Lang, Lee Marshall, Meghan Schilthuis, Jared Lamp, Irving Vega, Viviane Labrie. Hemispheric asymmetry in the human brain and in Parkinson's disease is linked to divergent epigenetic patterns in neurons. Genome Biology, 2020; 21 (1) DOI: 10.1186/s13059-020-01960-1

-- submitted from IRC


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  • (Score: 2) by ikanreed on Friday April 17 2020, @12:56PM (3 children)

    by ikanreed (3164) Subscriber Badge on Friday April 17 2020, @12:56PM (#984092) Journal

    The content is just fine, but "right brained" is a meaningless myth. Why the right brain has a marginally different structure from the left? That's what this answers.

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  • (Score: 2) by zeigerpuppy on Friday April 17 2020, @09:54PM (2 children)

    by zeigerpuppy (1298) on Friday April 17 2020, @09:54PM (#984334)

    you beat me too it! agreed, there are structural differences in the barin that nearly all of us have (whether we're right handed, "creative" or "technical") but the idea that people are "dominant" in one side is just persistent psychobabble.

    • (Score: 2) by barbara hudson on Friday April 17 2020, @11:35PM (1 child)

      by barbara hudson (6443) <barbara.Jane.hudson@icloud.com> on Friday April 17 2020, @11:35PM (#984371) Journal

      the idea that people are "dominant" in one side is just persistent psychobabble.

      So how do you explain the existence of handedness, of being left-handed persisting during times when it was regarded as evil and sinister and defective, and dominant eye, ear, leg. Or that being ambidextrous isn't the default if both hemispheres are equal?

      --
      SoylentNews is social media. Says so right in the slogan. Soylentnews is people, not tech.
      • (Score: 0) by Anonymous Coward on Saturday April 18 2020, @05:03PM

        by Anonymous Coward on Saturday April 18 2020, @05:03PM (#984607)

        What about nutcases that can't tell if they are male or female (know anyone like that TRANNY)? What happened barbara hudson? Did you shoot your mouth off only to have it slammed shut by APK https://soylentnews.org/comments.pl?noupdate=1&sid=33430&page=1&cid=889582#commentwrap [soylentnews.org] ? Yes. Go AWAY "TraNsTesTiCuLaR MONSTROSITY".