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posted by janrinok on Tuesday April 28 2020, @05:24AM   Printer-friendly
from the nom-nom-nom dept.

Good news for the wheat-sensitive among us: New research has heralded a promising step for sufferers of wheat sensitivity or allergy.:

A joint project between Edith Cowan University (ECU) in Australia and CSIRO has revealed key insights about the proteins causing two of the most common types of wheat sensitivity -- non-coeliac wheat sensitivity and occupational asthma (baker's asthma).

With an estimated 10 per cent of people suffering from wheat sensitivity or allergy causing a raft of chronic health issues, researchers are developing tests that will help the production of low-allergen wheat varieties in the future.

[...] "We have known for a long time that certain wheat proteins can trigger an immune response in some people, but now we have developed a way to detect and quantify these proteins," Professor Colgrave said.

"We looked [at] a group of proteins called alpha-amylase/trypsin inhibitors (ATIs), which are known to trigger the intestinal inflammation and chronic ailments associated with wheat intolerance in some people.

"These ATI proteins are commonly found in wheat and play an important role in plant defence against pests and also act as an important nutrient for plant growth and human nutrition."

Journal Reference:
Utpal Bose, Angéla Juhász, James A. Broadbent, Keren Byrne, Crispin A. Howitt, Michelle L. Colgrave. Identification and Quantitation of Amylase Trypsin Inhibitors Across Cultivars Representing the Diversity of Bread Wheat. Journal of Proteome Research, 2020; DOI: 10.1021/acs.jproteome.0c00059


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  • (Score: 2) by DeathMonkey on Tuesday April 28 2020, @05:38PM

    by DeathMonkey (1380) on Tuesday April 28 2020, @05:38PM (#987926) Journal

    Wheat allergy [mayoclinic.org]

    Diagnosis
    A physical exam, detailed medical history and some tests will help your doctor make a diagnosis. Tests or diagnostic tools may include:

    Skin test. Tiny drops of purified allergen extracts — including extracts for wheat proteins — are pricked onto your skin's surface, either on your forearm or on your upper back. After 15 minutes, your doctor or nurse looks for signs of allergic reactions.

    If you develop a red, itchy bump where the wheat protein extract was pricked onto your skin, you may be allergic to wheat. The most common side effect of these skin tests is itching and redness.

    Blood test. If a skin condition or possible interactions with certain medications prevent you from having a skin test, your doctor may order a blood test that screens for specific allergy-causing antibodies to common allergens, including wheat proteins.
    Food diary. Your doctor may ask you to keep a detailed record of what and when you eat and when symptoms develop for a time.
    Elimination diet. Your doctor may recommend that you remove certain foods from your diet, particularly those that are common allergens. Under your doctor's direction, you will gradually add foods back and note when symptoms return.
    Food challenge testing. You eat food suspected of being the allergy-causing agent while being monitored for allergy symptoms. Under supervision, you begin with a small amount of the food and gradually increase the amount you consume.

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