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posted by Fnord666 on Thursday May 14 2020, @06:10PM   Printer-friendly
from the Coffee:-it-calms-you-down-as-it-picks-you-up! dept.

Excess coffee consumption a culprit for poor health

Cappuccino, latte or short black, coffee is one of the most commonly consumed drinks in the world. But whether it’s good or bad for your health can be clarified by genetics, as a world-first study from the University of South Australia’s Australian Centre for Precision Health shows that excess coffee consumption can cause poor health.

Using data from over 300,000 participants in the UK Biobank, researchers examined connections between genetically instrumented habitual coffee consumption and a full range of diseases, finding that too much coffee can increase the risk of osteoarthritis, arthropathy (joint disease) and obesity.

In earlier research conducted by Professor Hyppönen and team, six cups of coffee a day were considered the upper limit of safe consumption.

Expert genetic epidemiologist, UniSA’s Professor Elina Hyppönen, says understanding any risks associated with habitual coffee intakes could have very large implications for population health.

[...] “In this study, we used a genetic approach – called MR-PheWAS analysis – to establish the true effects of coffee consumption against 1117 clinical conditions.

“Reassuringly, our results suggest that, moderate coffee drinking is mostly safe.

“But it also showed that habitual coffee consumption increased the risks of three diseases: osteoarthritis, arthropathy and obesity, which can cause significant pain and suffering for individuals with these conditions.”

[...] “For people with a family history of osteoarthritis or arthritis, or for those who are worried about developing these conditions, these results should act as a cautionary message.

[...] “While these results are in many ways reassuring in terms of general coffee consumption, the message we should always remember is consume coffee in moderation – that’s the best bet to enjoy your coffee and good health too.”

Journal Reference:
Konstance Nicolopoulos, Anwar Mulugeta, Ang Zhou, Elina Hyppönen. Association between habitual coffee consumption and multiple disease outcomes: A Mendelian randomisation phenome-wide association study in the UK Biobank. Clinical Nutrition, 2020; DOI: 10.1016/j.clnu.2020.03.009


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  • (Score: 2, Informative) by Anonymous Coward on Thursday May 14 2020, @10:48PM (1 child)

    by Anonymous Coward on Thursday May 14 2020, @10:48PM (#994429)

    I went to the journal paper so as to defend the researchers, since they aren't here to defend themselves. Unfortunately, most of the comments here are correct. This looks to be a bunch of people self-reporting and answering questions on tablets, then throwing it all into R to do some fancy statistical tests (Mendelian randomisation, phenome-wide association analyses, etc.). No, they didn't seem to ask about whether they take sugar or cream or whatever. I'm not going to try helping these guys out.

    Here is something from their Methods section

    Information on habitual coffee intake (cups/day) was collected at baseline using the touchscreen questionnaire and a question ‘How many cups of coffee do you drink each day (include decaffeinated coffee)?’ If participants reported that they drink less than one cup of coffee per day, we assigned a value of 0.5. A small number of participants (N = 279) reported very high coffee intake (>15 cups/day), with these outliers grouped together as 15 cups/day. We also constructed a categorical phenotype, for which participants were grouped into seven categories according to their daily coffee intake, namely non-drinkers, those drinking decaffeinated coffee, and those drinking caffeinated coffee with further sub-grouping based on the average daily amount (6 cups).
    Starting Score:    0  points
    Moderation   +2  
       Interesting=1, Informative=1, Total=2
    Extra 'Informative' Modifier   0  

    Total Score:   2  
  • (Score: 2) by looorg on Friday May 15 2020, @12:28AM

    by looorg (578) on Friday May 15 2020, @12:28AM (#994448)

    Your comment was probably more interesting then the paper then. In some regard it just makes it all much worse. If they had a touchscreen questionnaire and they couldn't be bother to program in more then "number of cups"? That is just fucking lazy. It would have been so easy to just ask how much suger, milk, other things etc to. That said 15 cups seems a bit on the high side, I don't think I drink 15 cups of anything in any given day really -- there are probably some hot days when I do but then it's not coffee.