SoylentNews is people
SoylentNews
Virginia Tech drug researcher develops 'fat burning' molecule that has implications for treatment of obesity (Science Daily)
"Obesity is the biggest health problem in the United States. But, it is hard for people to lose weight and keep it off; being on a diet can be so difficult. So, a pharmacological approach, or a drug, could help out and would be beneficial for all of society," said Webster Santos, professor of chemistry and the Cliff and Agnes Lilly Faculty Fellow of Drug Discovery in the College of Science at Virginia Tech.
Santos and his colleagues have recently identified a small mitochondrial uncoupler, named BAM15, that decreases the body fat mass of mice without affecting food intake and muscle mass or increasing body temperature. Additionally, the molecule decreases insulin resistance and has beneficial effects on oxidative stress and inflammation.
The findings, published in Nature Communications on May 14, 2020, hold promise for future treatment and prevention of obesity, diabetes, and especially nonalcoholic steatohepatitis (NASH), a type of fatty liver disease that is characterized by inflammation and fat accumulation in the liver. In the next few years, the condition is expected to become the leading cause of liver transplants in the United States.
Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice (open, DOI: 10.1038/s41467-020-16298-2) (DX)
Mitochondrial uncoupler BAM15 inhibits artery constriction and potently activates AMPK in vascular smooth muscle cells (open, DOI: 10.1016/j.apsb.2018.07.010) (DX)
BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control (open, DOI: 10.15252/emmm.202012088) (DX)
(Score: -1, Spam) by Anonymous Coward on Saturday June 13 2020, @09:52AM
This has been a public service announcement from GNAA (GAY NIGGER ASSOCIATION OF AMERICA).
And now we return to our usual broadcast...
GNAA (GAY NIGGER ASSOCIATION OF AMERICA) is the first organization which gathers GAY NIGGERS from all over America and abroad for one common goal - being GAY NIGGERS.
Are you GAY [klerck.org]?
Are you a NIGGER [mugshots.org]?
Are you a GAY NIGGER [gay-sex-access.com]?
If you answered "Yes" to any of the above questions, then GNAA (GAY NIGGER ASSOCIATION OF AMERICA) might be exactly what you've been looking for!
Join GNAA (GAY NIGGER ASSOCIATION OF AMERICA) today, and enjoy all the benefits of being a full-time GNAA member.
GNAA (GAY NIGGER ASSOCIATION OF AMERICA) is the fastest-growing GAY NIGGER community with THOUSANDS of members all over United States of America. You, too, can be a part of GNAA if you join today!
Why not? It's quick and easy - only 3 simple steps!
First, you have to obtain a copy of GAY NIGGERS FROM OUTER SPACE THE MOVIE [imdb.com] and watch it.
Second, you need to succeed in posting a GNAA "first post" on SoylentNews [soylentnews.org], a popular "news for trolls" website
Third, you need to join the official GNAA irc channel #GNAA on EFNet, and apply for membership.
Talk to one of the ops or any of the other members in the channel to sign up today!
If you are having trouble locating #GNAA, the official GAY NIGGER ASSOCIATION OF AMERICA irc channel, you might be on a wrong irc network. The correct network is EFNet, and you can connect to irc.prison.net or irc.colosolutions.net as one of the EFNet servers.
If you do not have an IRC client handy, you are free to use the GNAA Java IRC client by clicking here [nero-online.org].
If you have mod points and would like to support GNAA, please moderate this post up.
This post proudly brought to you by the GNAA president
________________________________________________
| ______________________________________._a,____ |
| _______a_._______a_______aj#0s_____aWY!400.___ |
| __ad#7!!*P____a.d#0a____#!-_#0i___.#!__W#0#___ |
| _j#'_.00#,___4#dP_"#,__j#,__0#Wi___*00P!_"#L,_ |
| _"#ga#9!01___"#01__40,_"4Lj#!_4#g_________"01_ |
| ________"#,___*@`__-N#____`___-!^_____________ |
| _________#1__________?________________________ |
| _________j1___________________________________ |
| ____a,___jk_GAY_NIGGER_ASSOCIATION_OF_AMERICA_ |
| ____!4yaa#l___________________________________ |
| ______-"!^____________________________________ |
` _______________________________________________'