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posted by chromas on Wednesday June 17 2020, @02:20PM   Printer-friendly

Amazingly Detailed Map Reveals How the Brain Changes With Aging:

Last week, in a technological tour-de-force, a European team from the United Kingdom, France, and Sweden, led by Dr. Seth G.N. Grant at the University of Edinburgh, redefined impossibility with a paper in Science. Peering into the brains of mice at different ages—one day, one week, and all the way up to an elderly 18 months—the team constructed maps of roughly 5 billion synapses, outlining a timeline of their diversity and numbers in over 100 different brain regions with age.

[...] In their new study, the team built a time map of synapses in the mouse brain, which they call the “lifespan synaptome architecture,” or LSA. The project is part of the Mouse Lifespan Synaptome Atlas, which comes with an assortment of tools for researchers to dig into to better understand how our brains age with time.

To build their synaptic timeline, the team analyzed the brain of a type of transgenic mice that have some proteins in their synapses highlighted with a fluorescent protein. The team picked ten points in their lifespan, covering the entire range of newly born to adolescent to adulthood and the elderly.

Journal Reference:
Mélissa Cizeron, Zhen Qiu, Babis Koniaris, et al. A brain-wide atlas of synapses across the mouse lifespan [$], Science (DOI: 10.1126/science.aba3163)


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  • (Score: 3, Funny) by DannyB on Wednesday June 17 2020, @05:00PM (4 children)

    by DannyB (5839) Subscriber Badge on Wednesday June 17 2020, @05:00PM (#1009203) Journal

    Now that Vulcan is downsizing, I wonder what is going to happen to his brain mapping project
    and to all of the research they've done.

    Substitute Ferengi brains. Continue research. Accumulating new results (on Ferengi brains) to existing results (on Vulcan brains).

    Publish.

    See if anyone will notice.

    Everyone happy.

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    People today are educated enough to repeat what they are taught but not to question what they are taught.
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  • (Score: 0) by Anonymous Coward on Wednesday June 17 2020, @05:18PM (2 children)

    by Anonymous Coward on Wednesday June 17 2020, @05:18PM (#1009208)

    > Kelloggs Corn Flakes, while commercially successful, was a total failure at preventing masturbation.

    ??

    • (Score: 1, Funny) by Anonymous Coward on Wednesday June 17 2020, @05:20PM

      by Anonymous Coward on Wednesday June 17 2020, @05:20PM (#1009209)

      You've clearly been eating them wrong.

    • (Score: 3, Informative) by DannyB on Wednesday June 17 2020, @07:15PM

      by DannyB (5839) Subscriber Badge on Wednesday June 17 2020, @07:15PM (#1009250) Journal

      It was two Kelloggs brothers. About 1900 or thereabout. One ran an institution for the criminally insane. The other created the cereal to help control various urges at the other brother's request. One or both of them were Seventh Day Adventists. There are more details, as I seem to recall, on Wikipedia.

      https://en.wikipedia.org/wiki/Corn_flakes [wikipedia.org]

      --
      People today are educated enough to repeat what they are taught but not to question what they are taught.
  • (Score: 2) by captain normal on Wednesday June 17 2020, @06:14PM

    by captain normal (2205) on Wednesday June 17 2020, @06:14PM (#1009227)

    Most will not notice because the results will be buried behind a paywall.

    --
    When life isn't going right, go left.