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Derek Lowe over at Science has a roundup of the status of current (article published 29 June 2020) Coronavirus vaccine trials/research.
This roundup of current vaccine research/trials includes information about many vaccine trials, broken down by vaccine types. These types include (quotes are all from TFA:
- Viral Vectors
This class uses some other infectious virus, but with its original genetic material removed. In its place goes genetic instructions to make coronavirus proteins, and when your infected cells do that, it will set off an immune response.
Number of trials (per TFA): 9
- Genetic Vaccines
These take DNA or RNA coding for coronavirus proteins and inject that directly into the bloodstream. "Directly" isn't quite the right word, though – for these things to work, they have to be formulated and modified to survive destruction in the blood, to be taken up through cell membranes, and to be used for protein production once they're inside.
Number of trials (per TFA): 8
- Recombinant protein vaccines
Here we get to a technique that really is used for human vaccines. The previous two categories force your own cells to make viral antigen proteins, but here you're making them industrially and just injecting them directly. The advantage can be that such protein production can be accomplished in many different ways and is already done on a large scale. That said, every new protein is a new project, with its own idiosyncrasies.
Number of trials (per TFA): 6
- Attenuated Virus Vaccines
This is another well-precedented vaccination technique. It involves producing a weakened form of the actual infectious virus, one that is not capable of causing damage but can still set off the immune system. There are several ways to do this, and it's a bit of an art form involving taking the virus through a huge number of replications in living cells as you select for variants that are less and less harmful.
Number of trials (per TFA): (None listed)
- Inactivated Virus Vaccines
This is also one that's also been used in medical practice for many years, and it's another inactivation step beyond the attenuated viruses. Heat or chemical agents are used to damage the virus to the point that it can no longer infect cells at all, but the plan is for there to be enough of the viral material left unaltered to still raise an immune response.
Number of trials (per TFA): 4
(Score: -1, Troll) by Anonymous Coward on Saturday July 04 2020, @01:40AM (15 children)
Yeah, except dumb ass protesters fucking it up for everyone. I predicted the numbers would start spiking a few weeks after the protests started. Sure enough here it is.
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(Score: 5, Informative) by Thexalon on Saturday July 04 2020, @01:43AM (11 children)
There have been multiple studies on this: There is no evidence at all that protests have been what's been spreading Covid-19. The protesters you're talking about for the most part have been socially distancing and wearing masks and are outdoors. You're basically relying entirely on post hoc ergo propter hoc, which isn't actually proof of anything.
What's definitely a factor is large gatherings indoors. For example, attending one of those with sick people present is why Herman Cain is now in the hospital.
The only thing that stops a bad guy with a compiler is a good guy with a compiler.
(Score: -1, Troll) by Anonymous Coward on Saturday July 04 2020, @01:47AM (4 children)
No, the protesters here in SoCal were not wearing masks and were not socially distancing while they looted and burn't down historic buildings. And the spike in cases is also right here.
(Score: 5, Informative) by barbara hudson on Saturday July 04 2020, @03:05AM (3 children)
But that's okay - the cops die at an average age of 60 from pre-existing conditions - 80% die from obesity and heart disease. Help save a pigs fife - defund the police so they have to get an honest job that requires them to get off their obese butts.
SoylentNews is social media. Says so right in the slogan. Soylentnews is people, not tech.
(Score: 0) by Anonymous Coward on Saturday July 04 2020, @02:39PM
"Help save a pigs fife"
STOP THE MUSIC!
(Score: 3, Interesting) by Anonymous Coward on Saturday July 04 2020, @03:45PM (1 child)
You weren't there, I saw the bullshit go down 3 nights in a row from my yard. Both antifa and white trash came in from other areas, were in large groups across the street from each other, no masks, and lots of clashes between them. You don't see this shit on the news coverage.
(Score: 0) by Anonymous Coward on Saturday July 04 2020, @11:16PM
You only hear about it from Anecdotal Cowards.
(Score: 2, Funny) by Anonymous Coward on Saturday July 04 2020, @02:20AM (1 child)
That is the most amazing virus ever. It knows if you are protesting and will not spread!
(Score: 5, Informative) by Tork on Saturday July 04 2020, @06:23AM
Masks work.
🏳️🌈 Proud Ally 🏳️🌈
(Score: 1, Troll) by ChrisMaple on Saturday July 04 2020, @02:59AM (2 children)
Rioters, as distinct from protestors, try to ensure that they're not recognized. Claims to trace them and their contacts must be considered unfounded.
In any case, these things aren't spontaneous.They're planned in untelevised, unrecorded meetings, most likely in small hidden places. Perfect for transmission. Keep in mind that these are people who want to make trouble, so the desire to spread the disease is limited only by the desire to not be personally infected.
(Score: 5, Insightful) by Anonymous Coward on Saturday July 04 2020, @03:07AM (1 child)
You mean, on Twitter and by text?
These are people who live in fear for their lives. In my country, we have first nations without safe drinking water supplies. They "make trouble" too. George Floyd "made trouble" when he cried for help, and for his mother, as he died.
You're either evil or clueless. I hope the latter, in which case, please go do some reading. Maybe investigate disparities in other nations - Indigenous communities in Colombia and First Nations in Canada, off the cuff - so that your personal local biases get less in the way of seeing the truth.
(Score: 5, Interesting) by Azuma Hazuki on Saturday July 04 2020, @03:18AM
There is a point where Hanlon's Razor ("do not attribute to malice what may be explained by stupidity") loses its edge. At some point, willful ignorance becomes malicious. The AC you're replying to has long since passed this point.
I am "that girl" your mother warned you about...
(Score: 1, Insightful) by Anonymous Coward on Saturday July 04 2020, @03:22AM
There have been weeks of protests, CHAZzes and CHOPs since June. It's too soon for peer unreviewed "studies" to exonerate them.
(Score: 2, Interesting) by Anonymous Coward on Saturday July 04 2020, @12:43PM (2 children)
The parent shouldn't be modded as spam. Someone needs to be punished abusing the spam mod.
According to the actual experts, a person needs to be exposed to quantities of the virus above some threshold in order to actually develop an infection. Weaker exposures won't result in an infection. Masks greatly reduce the extent to which infected people shed the virus. Outdoors, especially with any breeze, the virus is readily dispersed into the air, rapidly decreasing the concentration of the virus in any particular location.
There's considerable hypocrisy from a lot of people on the issue of spreading the virus outdoors. People are happy to condemn people attending outdoor parties and going to crowded beaches, saying they're being selfish and causing cases to surge. But some of these people are happy to defend the protesters. Many people on the right are quick to condemn Black Lives Matter protests but fail to mention the many people on the right who are attending counter-protests. A lot of the criticism seems to be politically motivated, not based on actual science. Otherwise, we would be more consistent about whether large outdoor gatherings are safe or not.
There were large protests in cities like New York, where cases haven't surged at all. There were also large protests in areas where cases are surging rapidly. If protests were the primary factor, shouldn't cases be surging everywhere protests occurred? The same goes for other large outdoor gatherings, which occur both in places where cases are surging and places where cases have not surged. At least in some states, cases are surging more in rural areas than urban areas.
There is undoubtedly some risk of spreading the virus outdoors in large crowds, but the data and the science just don't support this being a primary cause of cases surging. It's more likely that there's some contribution from the reopening of certain types of businesses such as bars. The uneven distribution of cases may also reflect demographic and cultural differences that affect people's willingness to follow guidance from government officials and scientists about how to prevent the spread of the virus. Where people are more likely to distrust those authority figures, they may be less willing to comply with recommendations like social distancing and masks. But I'd much rather have people gathering outdoors on beaches or in protests instead of gathering indoors. The risk isn't zero, but it appears to be much lower.
(Score: 0, Disagree) by Anonymous Coward on Saturday July 04 2020, @03:47PM (1 child)
New York was already at herd immunity levels before the riots started. Nice try.
(Score: 3, Informative) by NotSanguine on Saturday July 04 2020, @04:06PM
Where is the evidence for this? Or is it that because *you* said it, it must be true?
Except the data [ny.gov] doesn't bear out your statement.
So. You're either misinformed or lying. Which one is it?
No, no, you're not thinking; you're just being logical. --Niels Bohr