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Derek Lowe over at Science has a roundup of the status of current (article published 29 June 2020) Coronavirus vaccine trials/research.
This roundup of current vaccine research/trials includes information about many vaccine trials, broken down by vaccine types. These types include (quotes are all from TFA:
- Viral Vectors
This class uses some other infectious virus, but with its original genetic material removed. In its place goes genetic instructions to make coronavirus proteins, and when your infected cells do that, it will set off an immune response.
Number of trials (per TFA): 9
- Genetic Vaccines
These take DNA or RNA coding for coronavirus proteins and inject that directly into the bloodstream. "Directly" isn't quite the right word, though – for these things to work, they have to be formulated and modified to survive destruction in the blood, to be taken up through cell membranes, and to be used for protein production once they're inside.
Number of trials (per TFA): 8
- Recombinant protein vaccines
Here we get to a technique that really is used for human vaccines. The previous two categories force your own cells to make viral antigen proteins, but here you're making them industrially and just injecting them directly. The advantage can be that such protein production can be accomplished in many different ways and is already done on a large scale. That said, every new protein is a new project, with its own idiosyncrasies.
Number of trials (per TFA): 6
- Attenuated Virus Vaccines
This is another well-precedented vaccination technique. It involves producing a weakened form of the actual infectious virus, one that is not capable of causing damage but can still set off the immune system. There are several ways to do this, and it's a bit of an art form involving taking the virus through a huge number of replications in living cells as you select for variants that are less and less harmful.
Number of trials (per TFA): (None listed)
- Inactivated Virus Vaccines
This is also one that's also been used in medical practice for many years, and it's another inactivation step beyond the attenuated viruses. Heat or chemical agents are used to damage the virus to the point that it can no longer infect cells at all, but the plan is for there to be enough of the viral material left unaltered to still raise an immune response.
Number of trials (per TFA): 4
(Score: 0, Troll) by ChrisMaple on Saturday July 04 2020, @02:43AM (13 children)
The states with explosive coronavirus infection rates are California, Arizona, Texas, Florida, and Georgia. All are deep south states and the first three have serious problems with uncontrolled illegal immigration. The illegal immigration problem sits in the lap of Democrats. I suspect that some people are having to choose between risking coronavirus infection by not wearing a mask, and heat stroke by wearing a mask.
(Score: 5, Informative) by Azuma Hazuki on Saturday July 04 2020, @03:19AM (7 children)
Isn't it usually the GOP types who love all that virtual slave labor they get from massive illegal immigration?
I am "that girl" your mother warned you about...
(Score: 0) by Anonymous Coward on Saturday July 04 2020, @04:21AM
Hey now, don't stoop to ChrisMaple's politicizing. But yes, we love to look at well-kept lawns and gardens. And eat harvested food.
(Score: 2, Insightful) by Anonymous Coward on Saturday July 04 2020, @06:49AM (5 children)
Shhh, don't point out Schrodinger's immigrants or their cognitive dissonance will collapse. You know, the one about how they are taking all our jobs and are inherently lazy at the same time. Where they are drug-running criminals and the cornerstone of our agricultural and construction industries.
(Score: 2) by Azuma Hazuki on Saturday July 04 2020, @07:25PM (4 children)
I always did wonder about that, LOL. Like, how can Paco and Jose and Ramon be simultaneously stealing jobs and leeching off the welfare and unemployment? That's not physically possible.
I am "that girl" your mother warned you about...
(Score: 0) by Anonymous Coward on Saturday July 04 2020, @08:19PM (1 child)
Correct, not unemployment, but yes medical system.
(Score: 0) by Anonymous Coward on Saturday July 04 2020, @11:37PM
Yet another reason for universal healthcare, also just FYI most immigrants do pay taxes.
https://americasvoice.org/blog/immigration-101-immigrant-taxes/ [americasvoice.org]
The non-tax-paying lie is just another bit of misinformation to keep people angry at illusory problems. If they didn't pay taxes it would be TOO EASY to catch them.
(Score: 0) by Anonymous Coward on Saturday July 04 2020, @08:31PM (1 child)
oh they shamelessly get all kinds of benefits while working full time. i know because they've laughed about it to me. there are whole organizations dedicated to stealing from whitey.
(Score: 0) by Anonymous Coward on Saturday July 04 2020, @10:33PM
You mean, Banks? Apple? White Claw? Could you be more specific?
(Score: 1, Insightful) by Anonymous Coward on Saturday July 04 2020, @03:32AM
You are a fucking loon.
CA and AZ deep south states? Illegal immigration sits in the lap of Dems? Lawl you nutters just continue to deliver on the entertaining stupidity. Sadly it adds up to real life persecution of real people, so go fuck yourself for that part!
(Score: 2) by sjames on Saturday July 04 2020, @04:16AM
So many things wrong with your claims. Ca and Az are not Deep South. Tx is only sort of Deep South. All but Ca are red states. A mask isn't going to cause heat stroke.
(Score: 2) by PiMuNu on Saturday July 04 2020, @06:31AM
How does illegal immigration cause coronavirus?
(Score: 0) by Anonymous Coward on Saturday July 04 2020, @08:09AM
Georgia... deep south, eh? Next time, don't keep your marbles together with you compass, it seems you are prone to lose the latter quite easily.
(Score: 2) by HiThere on Saturday July 04 2020, @03:51PM
Immigration is irrelevant, when the US case load is so high. I think the key is "southern". I.e. places where it's warm and nice to be outside in groups of people. Outside is less infectious, but people don't STAY outside, and meet, gather, greet friends, and go some place together. This is encouraged by warm weather. Also by hot weather, though then people tend to congregate where there is cool-enough air conditioning. Like bars, theaters, etc.
One key thing that showed up early is that air flow patterns can be important in whether and how COVID spreads. That originally showed up in the early Wuhan restaurant case, where someone sitting at a different table caught the disease, and not everyone at the same table did. (Of course, some people don't have symptoms, and this was before there was any testing, so???)
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