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Derek Lowe over at Science has a roundup of the status of current (article published 29 June 2020) Coronavirus vaccine trials/research.
This roundup of current vaccine research/trials includes information about many vaccine trials, broken down by vaccine types. These types include (quotes are all from TFA:
- Viral Vectors
This class uses some other infectious virus, but with its original genetic material removed. In its place goes genetic instructions to make coronavirus proteins, and when your infected cells do that, it will set off an immune response.
Number of trials (per TFA): 9
- Genetic Vaccines
These take DNA or RNA coding for coronavirus proteins and inject that directly into the bloodstream. "Directly" isn't quite the right word, though – for these things to work, they have to be formulated and modified to survive destruction in the blood, to be taken up through cell membranes, and to be used for protein production once they're inside.
Number of trials (per TFA): 8
- Recombinant protein vaccines
Here we get to a technique that really is used for human vaccines. The previous two categories force your own cells to make viral antigen proteins, but here you're making them industrially and just injecting them directly. The advantage can be that such protein production can be accomplished in many different ways and is already done on a large scale. That said, every new protein is a new project, with its own idiosyncrasies.
Number of trials (per TFA): 6
- Attenuated Virus Vaccines
This is another well-precedented vaccination technique. It involves producing a weakened form of the actual infectious virus, one that is not capable of causing damage but can still set off the immune system. There are several ways to do this, and it's a bit of an art form involving taking the virus through a huge number of replications in living cells as you select for variants that are less and less harmful.
Number of trials (per TFA): (None listed)
- Inactivated Virus Vaccines
This is also one that's also been used in medical practice for many years, and it's another inactivation step beyond the attenuated viruses. Heat or chemical agents are used to damage the virus to the point that it can no longer infect cells at all, but the plan is for there to be enough of the viral material left unaltered to still raise an immune response.
Number of trials (per TFA): 4
(Score: 2) by Azuma Hazuki on Saturday July 04 2020, @07:53PM (8 children)
Hasn't it occurred to you yet that I'm not a "joiner?" I do my own thing. The group that loosely calls itself "the left" tends to be largely correct on most things (reality has a liberal bias by default, since "conservatism" entails tribalism and loyalty uber alles). But where they are wrong, I have no problem breaking ranks and telling them as much.
You are a worthless, shit-stirring troll, and not even a very good one at that. Your schtick is much too transparent and overplayed; the lack of subtlety causes people not to take you seriously. A good Poe should be indistinguishable enough from what it's attempting to satirize that most of the audience isn't sure whether it's satire or not.
I am "that girl" your mother warned you about...
(Score: 0) by Anonymous Coward on Saturday July 04 2020, @08:07PM (2 children)
Leave the outdated comedic quips to the has-been comedians.
(Score: 2) by Azuma Hazuki on Saturday July 04 2020, @08:14PM (1 child)
I am as deadly serious as an incoming asteroid the size of Rhode Island, and this pandemic bears that observation out. "Conservatism" as a culture brings with it an emphasis on in-group loyalty and obedience so powerful than actual objective reality all too often falls by the wayside.
"Liberal" states are the ones weathering this disaster the best; look no further than New York State and especially NYC proper, my beloved and much-missed hometown, compared to...well, pretty much anywhere south of the Mason-Dixon line. The next couple of months are going to be a sea of virus-ridden blood in the Peoples' Republic of Cousinfuckistan, and as a direct result of "conservative" tendency to prioritize obedience and groupthink above independent thought.
I am "that girl" your mother warned you about...
(Score: 0) by Anonymous Coward on Saturday July 04 2020, @11:02PM
While convincing themselves they are the exact opposite.
(Score: 1) by NPC-131072 on Saturday July 04 2020, @08:18PM (4 children)
I think to be on the morally superior left is to distinguish yourself from the position you just took.
(Score: 0) by Anonymous Coward on Saturday July 04 2020, @11:14PM
Ok sock puppet, please give us more of your cloth based wisdom.
(Score: 2) by Azuma Hazuki on Saturday July 04 2020, @11:23PM (2 children)
And what you "think" isn't worth the proverbial fetid pair of dingo's kidneys, as you've shown yourself to be a troll--a poor one, at that--from day one. No one on this site cares what you claim you think, and that word is much too charitable a use for what it is you're actually doing.
I am "that girl" your mother warned you about...
(Score: 0) by Anonymous Coward on Saturday July 04 2020, @11:32PM
HEY!
I care. I love shitting on idiots :D
(Score: 0, Troll) by NPC-131072 on Saturday July 04 2020, @11:52PM
I think Azuma Vs. Leftism is exactly why we'll never be frens.