SoylentNews is people
SoylentNews
According to research published in the Journal of Clinical Pychopharmacology a double-blind clinical trial has shown that microdoses of LSD are effective at reducing pain.
With just three non-hallucinogenic "micro"doses, participants displayed what seemed to be an increase in pain tolerance and a decrease in subjective perceptions of pain. This prolonged response, the authors claim, is on par with up to 20 mg of oxycodone or morphine.
The size of the dosage, however, did matter. Any amount of LSD lower than 20 µg (which is considered a relatively large microdose among online users) did not seem to have this reported analgesic effect.
"The present data suggest that low doses of LSD might constitute a novel pharmacological therapy that can be efficacious in patients and is devoid of problematic sequelae [(chronic complications)] that are associated with current mainstay drugs, such as opioids," the authors conclude.
Existing research on LSD mechanisms is limited due to (now-relaxed) restrictions on its use in clinical trials; the underlying mechanism of the pain-reducing effect is not yet understood.
The authors conclude that the results "warrant further research."
Journal Reference:
A low dose of lysergic acid diethylamide decreases pain perception in healthy volunteers: [open], Journal of Psychopharmacology (DOI: 10.1177/0269881120940937)
(Score: 1) by fakefuck39 on Monday August 31 2020, @10:05PM (1 child)
Egh, shit happens. In my case it was boiling peanut oil on the stove, and the shit boiling over the top, firing up from the stove, and exploding all over me and the kitchen. And of course the french landlord I was renting from thought it was a good idea for the fire extinguisher to be nice and secure. As in walk out the door, go to the basement, unlock the basement door with a key, unlock a storage locker with a different key, and get the fire extinguisher. While you're on fire. Oh the French. Beautiful country, very polite.
So tramadol was actually created to not be addictive. I don't know more than your doctor, but my theory is you had too much serotonin, and that was making you all weird. It boost your serotonin. A way to counter that is to have less b6 or less htp in your diet. You can also take some velvet bean to boost your dopamine, which would lower serotonin since they compete for an enzyme. Hydrocodone is an american thing they don't use in europe. There's a reason for that - it's basically heroin with lower potency. I'd sick to tramadol. Can you explain what you meant by addictive - like did you have physical withdrawal symptoms? You're not supposed to have those with it.
Question though - why morphine injections? Unless you're already on a drip, why not just a 6 or 9mg pill? If it was right after an accident I'd understand an injection, but you're not supposed to feel high on it. If you're in pain, opiates don't make you high. If they do, you're getting way too large of a dose. It's supposed to just make you not feel pain or make you fall asleep.
Honestly if you got something where you're on pain killers for years, opiates aren't the way to go. Tramadol is designed not to be addictive, but not meant to be taken for over a year. But Hydrocodone is way way worse. Seriously - have you tried toking the mary jay? But like in a vape or eating it so you don't get cancer and suffocate from the smoke.
(Score: 2) by DannyB on Tuesday September 01 2020, @01:54PM
One thing about tramadol was that I was in a good mood. All the time. Constantly. That just isn't natural. But I'm glad I'm off it. That was back in 2010.
In the 70's, middle school, I had morphine from a broken wrist. In 2016 and 2017 I had morphine a couple times at the ER for kidney stones.
The AT&T organ harvesting was after waking up from some kind of sedative for an outpatient procedure.
What you describe is probably why my arthritis specialist gave me tramadol. He can also write opiate prescriptions, but I get those from my primary care doctor. I only use hydrocodone occasionally, not routinely. I take potent prescription nsaids and lots of acetaminophen every day. The opiate if it is really bad. Even then, I try starting with half a tablet. I don't take it often enough or in large enough doses to have any problems with constipation or tolerance. I realize that if I had to take that stuff regularly, that story does not have a very nice ending.
I have not tried any mary jay for decades. I program in Java instead.
The lower I set my standards the more accomplishments I have.